Trials Sponsors Conditions Drugs Pricing

Conditions

Temporomandibular Joint Disc Displacement, With Reduction

Keywords

tmjdisc displacement with reductionjaw trackinghyaluronic acidprpTemporomandibular DisordersZebrisJoint clickingMaximum Mouth OpeningIntra-articular Injection

Outcome Measures

Primary Outcomes (1)

Mandibular movements assessed using the zebris JMA
changes in mandibular movements assessed using the Zebris Jaw Motion Analyzer (JMA) system following treatment
Baseline, 1month

Secondary Outcomes (3)

Pain Assessment using the Visual Analogue Scale
baseline, 1 week, 1 month, 3months, 6 months
clicking sound
Baseline, 6 months

Study Arms (1)

Hyaluronic acid + PRP

EXPERIMENTAL

patients with disc displacement with reduction will undergo intra-articular injection with hyaluronic acid and prp

Combination Product: Hyaluronic Acid (HA) and Platelet rich plasma

Interventions

Hyaluronic Acid (HA) and Platelet rich plasmaCombination product

A combination of Autologous Platelet-Rich Plasma prepared from the patient's blood and hyaluronic acid injected intra-articularly

Hyaluronic acid + PRP

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 45 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64)

You may qualify if:

The patients' ages range from 18 to 45.
Patients experienced clicking sounds, painful joints, and restricted mouth opening.

Sponsors & Collaborators

Mansoura University
Otherlead

Study Sites (1)

Faculty of Dentistry, Mansoura university

Al Mansurah, Dakahlia Governorate, 35516, Egypt

MeSH Terms

Conditions

Temporomandibular Joint DisordersInsomnia, Fatal Familial

Interventions

Hyaluronic Acid

Condition Hierarchy (Ancestors)

Craniomandibular DisordersMandibular DiseasesJaw DiseasesMusculoskeletal DiseasesJoint DiseasesMuscular DiseasesStomatognathic DiseasesPrion DiseasesCentral Nervous System InfectionsInfectionsCentral Nervous System Diseases

Enrollment

20 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Masking Details: The clinical outcomes assessor and MRI assessor were blinded to the intervention details during outcome assessment.
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Oral and maxillofacial master student

Study Record Dates

First Submitted

June 7, 2026

First Posted

June 11, 2026

Study Start

July 1, 2025

Actual (reported)

Clinical and Jaw Tracking Assessment Following Intra-articular Injection of PRP and HA in TMJ Disc Displacement With Reduction

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (1)

Hyaluronic acid + PRP

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (1)

Hyaluronic acid + PRP

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations