Fall Injury Mortality Prediction

NCT07643051 | Completed

• 1 other identifier: 26MMHIS178e
• Study Type: observational
• Target: 58,353
• Locations: 0 countries
• Sites: N/A

Brief Summary

This retrospective, multicenter, registry-based cohort study used data from the Pan-Asian Trauma Outcomes Study registry between January 2016 and December 2024. Adult patients with fall-related trauma were included if they had available data on age, sex, emergency department vital signs, and 30-day mortality. The final cohort was randomly divided into derivation and validation cohorts in a 2:1 ratio. Candidate predictors were selected based on clinical relevance, field triage criteria, prior trauma literature, and early availability. Multivariable logistic regression was used to develop the model, and regression coefficients were converted into an integer-based score. Model performance was assessed using discrimination, calibration, Brier score, and threshold-based metrics.

Conditions

Trauma Injury; Mortality Prediction; Fall

Outcome Measures

Primary Outcomes (1)

• 30-day Mortality

  30-day Mortality

  30-day

Study Arms (1)

Fall injury group

adult patients with fall-related trauma

Other: Prediction model development

Interventions

Prediction model development OTHER

Prediction model development

Fall injury group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Among patients with traumatic injuries recorded in the PATOS registry between January 2016 and December 2024, those with fall-related injuries were screened for eligibility. Patients younger than 18 years and those with missing data on age, sex, ED vital signs, or 30-day mortality were excluded.

You may qualify if:

• Among patients with traumatic injuries recorded in the PATOS registry between January 2016 and December 2024, those with fall-related injuries were screened for eligibility.

You may not qualify if:

• Patients younger than 18 years and those with missing data on age, sex, ED vital signs, or 30-day mortality were excluded.

Sponsors & Collaborators

• Mackay Memorial Hospital: lead
• National Taiwan University Hospital, Yun-Lin Branch: collaborator
• Taipei Medical University: collaborator

MeSH Terms

Conditions

Accidental Injuries

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Attending Physician

Study Record Dates

• First Submitted: June 6, 2026
• First Posted: June 11, 2026
• Study Start: January 1, 2016
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: June 11, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share