NCT07641621

Brief Summary

The goal of this clinical trial is to learn if chiropractic ankle manipulation can improve squat jump performance. It will also learn about the relationship among chiropractic ankle manipulation, ankle range of motion, and squat jump performance. The main questions it aims to answer are:

  • Does chiropractic ankle manipulation increase squat jump height?
  • Is there a relationship among chiropractic ankle manipulation, ankle range of motion, and squat jump performance? Researchers will compare squat jump performance between subjects who receive chiropractic ankle manipulations with control subjects to see if ankle chiropractic manipulation works to improve squat jump performance. Participants will:
  • Visit the research laboratory for one testing session to measure ankle range of motion and squat jump performance, before and after their randomly assigned intervention arm
  • Receive either a chiropractic ankle manipulations or rest quietly as the control condition during the testing session.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
11mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress4%
Jun 2026May 2027

First Submitted

Initial submission to the registry

May 31, 2026

Completed
1 day until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 11, 2026

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2027

Last Updated

June 11, 2026

Status Verified

May 1, 2026

Enrollment Period

11 months

First QC Date

May 31, 2026

Last Update Submit

June 7, 2026

Conditions

Keywords

chiropracticmanipulationanklesquat jumpathletic performance

Outcome Measures

Primary Outcomes (2)

  • Squat Jump Height

    Subjects will be instructed to jump upwards from the starting squat position as high as possible. Subjects will perform 3 to 6 jumps with 3 consecutive jump heights being within 5% of each other to ensure maximum jump height is achieved. There will be a one-minute rest between jumps. * Starting position. Subjects will assume the starting squat position with their hips at 90°, knees at 120°, and ankles at 85° as positioned by the PI. An adjustable plyometric jump box will be used to standardize the starting position. Hands will be resting across their chest with the trunk and head positioned straight ahead. * Squat Jump: Subjects will be instructed to jump as high as possible and land in a comfortable position. Hands will remain across the chest for the duration of The Optojump photoelectric cell system (OptoJump) will be used to record jump height. OptoJump demonstrates strong concurrent validity and excellent test-retest reliability for the estimation of vertical jump height

    Baseline on Day 1 to Immediately after Intervention on Day 1

  • Range of Motion of Ankle Dorsiflexion

    Knee-to-wall ankle dorsiflexion test: * Ankle dorsiflexion ROM (distance from wall - cm) is the maximum distance of the big toe from the wall while maintaining contact between the wall and the knee with the heel on the ground. * The subject will repeat the Knee-to-wall ankle dorsiflexion test three times at this maximum distance to allow the PI to record three goniometer measurements of ankle dorsiflexion ROM (degrees°).

    Baseline on Day 1 to Immediately after Treatment on Day 1 and at End of Test Session on Day 1

Secondary Outcomes (3)

  • Leg Muscle Power (W/Kg)

    Baseline on Day 1 to Immediately after Intervention on Day 1

  • Contraction Velocity of Leg Muscles (mm/s), Force-Velocity Curve

    Baseline on Day 1 to Immediately after Intervention on Day 1

  • Rate of Force Development of Leg Muscles (N/s), Slope of the Force - Velocity Curve

    Baseline on Day 1 to Immediately after Intervention on Day 1

Study Arms (2)

Chiropractic Ankle Manipulation

EXPERIMENTAL

LEM - Lower Extremity Manipulation: Subjects assigned to the LEM Intervention Group will receive a short lever, high velocity, low-amplitude distractive (caudal) thrust directed at the talocrural joint. The treating chiropractor will deliver the LEM to the right ankle then the left ankle. LEM is an adjustment for long axis distraction of the tibiotalar joint with the goal to improve dorsiflexion of the ankle joint.

Other: Manual Therapy Procedure: Chiropractic Ankle Manipulation

Control

NO INTERVENTION

Subjects assigned to the Control Group will rest quietly, supine (face up), on the chiropractic treatment table for five (5) minutes.

Interventions

The lower extremity manipulation (LEM) procedure is a short lever, high velocity, low-amplitude distractive (caudal) thrust directed at the talocrural joint. The treating chiropractor will deliver the LEM to the right ankle then the left ankle. LEM is an adjustment for long axis distraction of the tibiotalar joint with the goal to improve dorsiflexion of the ankle joint.

Also known as: Lower Extremity Manipulation
Chiropractic Ankle Manipulation

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • age range from 18 to 35 years old; and
  • participating in recreational exercise, three times a week for at least 30 minutes. Recreational exercise includes ball sports (e.g. soccer, basketball, volleyball, etc.), racket sports (e.g. tennis, pickle ball, racket ball, etc.), strength/combat sports (e.g. weight lifting, boxing, martial arts, kickboxing, etc.), endurance sports (running, cycling, rock climbing, etc.), snow/ice sports (downhill or cross-county skiing, snow shoeing, hockey, etc.), interval training (e.g., high-intensity interval training), sprint interval training, repeated sprint training etc.) or moderate-intensity aerobic activities (step classes, dance classes, hiking, etc.)

You may not qualify if:

  • professional or amateur ranked athlete;
  • acute or chronic musculoskeletal injury / condition of the feet, ankles, knees, and/or hips;
  • acute or chronic musculoskeletal injury / condition of the spine;
  • pregnancy or there is a possibility of pregnancy.
  • any diagnosed medical condition; and
  • any prescribed medications with the exceptions of birth control, anxiety, or attention-deficit/hyperactivity disorder (ADHD) medications.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Biomechanics Laboratory at Northeast College of Health Sciences

Seneca Falls, New York, 13148, United States

Location

Central Study Contacts

Jeanmarie R Burke, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dean of Research

Study Record Dates

First Submitted

May 31, 2026

First Posted

June 11, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

May 1, 2027

Study Completion (Estimated)

May 1, 2027

Last Updated

June 11, 2026

Record last verified: 2026-05

Locations