Sideritis Supplementation and Performance

NCT07555288 | Not Yet Recruiting

• 1 other identifier: UTH_DPESS_SID_PER
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine the effect of sideritis consumption on physiological and performance indicators in adult subjects and compare it with the control trial.

Conditions

Athletic Performance

Keywords

sideritis; Extract; Performance; Blood lactate; Blood Glusose

Outcome Measures

Primary Outcomes (9)

• Change in Blood lactate

  Blood lactate concentration will be estimated using an analyzer.

  Change from baseline to 15, 30, 45, 60 minutes during exercise and immediately post-exercise

• Change in mean respiratory quotient during exercise

  The mean respiratory quotient during exercise will be measured using a gas analyzer

  Mean respiratory quotient will be measured during 60 minute of exercise

• Change in mean oxygen consumption during exercise

  Mean oxygen consumption during exercise will be measured using a gas analyzer

  Mean oxygen consumption will be measured during 60 minute of exercise

• Change in mean Heart rate during exercise

  Mean heart rate during exercise will be measured using a heart rate monitor

  Mean heart rate will be measured during 60 minute of exercise

• Change in time to exhaustion

  Time to exhaustion will be estimated using an electronic timer

  The time to exhaustion will be measured immediately after 60 minute of exercise

• Change in Glucose concentration

  Glucose concentration will be estimated using an analyzer.

  Change from baseline to 15, 30, 45, 60 minutes during exercise and immediately post-exercise

• Change in heart rate

  Heart rate will be estimated using monitor units.

  Change from baseline to 15, 30, 45, 60 minutes during exercise and immediately post-exercise

• Change in oxygen consumption

  Oxygen consumption will be estimated using gas analyzer

  Change from baseline to 15, 30, 45, 60 minutes during exercise and immediately post-exercise

• Change in respiratory quotient

  Respiratory quotient will be estimated using gas analyzer

  Change from baseline to 15, 30, 45, 60 minutes during exercise and immediately post-exercise

Secondary Outcomes (5)

• Body weight

  Baseline

• Body fat (%)

  Baseline

• Resting Heart Rate

  Baseline

• Diastolic and systolic blood pressure

  Baseline

• Maximal oxygen consumption (VO2max)

  Baseline

Study Arms (2)

Sideritis Scardica (SidTea+) extract

EXPERIMENTAL

Sideritis Scardica (SidTea+) extract will be administered to participants in this arm.

Dietary Supplement: 950 mg of Sideritis Scardica (SidTea+) extract one hour pre-exercise

Placebo Supplementation

PLACEBO COMPARATOR

Placebo will be administered to participants in this arm.

Dietary Supplement: 950 mg of placebo one hour pre-exercise

Interventions

950 mg of Sideritis Scardica (SidTea+) extract one hour pre-exercise DIETARY_SUPPLEMENT

950 mg of Sideritis Scardica (SidTea+) extract one hour pre-exercise during exercise day

Sideritis Scardica (SidTea+) extract

950 mg of placebo one hour pre-exercise DIETARY_SUPPLEMENT

950 mg of placebo one hour pre-exercise during exercise day

Placebo Supplementation

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy Individuals aged 18-40 years

You may not qualify if:

• Musculoskeletal Injury
• Dietary supplements
• Medication

Sponsors & Collaborators

• University of Thessaly: lead

Study Sites (1)

Exercise Biochemistry, Physiology and Nutrition Laboratory, Department of Physical Education and Sport Science, University of Thessaly

Trikala, Thessaly, 42150, Greece

Location

Related Publications (1)

• Papanikolaou K, Kouloridas K, Rosvoglou A, Gatsas A, Georgakouli K, Deli CK, Draganidis D, Argyropoulou A, Michailidis D, Fatouros IG, Jamurtas AZ. Characterization of the Sideritis scardica Extract SidTea+TM and Its Effect on Physiological Profile, Metabolic Health and Redox Biomarkers in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Molecules. 2024 Mar 1;29(5):1113. doi: 10.3390/molecules29051113.

  PMID: 38474625 BACKGROUND

Study Officials

• Athanasios Z Jamurtas, Professor

  University of Thessaly

  STUDY DIRECTOR

Central Study Contacts

Athanasios Jamurtas Z Jamurtas, Professor

CONTACT

24310 47054; ajamurt@uth.gr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: April 21, 2026
• First Posted: April 29, 2026
• Study Start: April 25, 2026
• Primary Completion (Estimated): May 25, 2026
• Study Completion (Estimated): May 30, 2026
• Last Updated: April 29, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

GR (1)