Optimizing Participation In Colorectal Cancer Screening By Direct Invitation Of Non Responders By General Practitionners

NCT07639554 | Not Yet Recruiting

• 1 other identifier: 2025-A01370-49
• Study Type: interventional
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this randomized trial is to assess the effectiveness of a targeted telephone reminder strategy, implemented by the patient's general practitioner, in enhancing participation in colorectal cancer screening among individuals who are not up to date . The participants are patients between 50 to 74 years old as they are the target for colorectal cancer screening. The main questions are:

• What is the percentage of patients who completed the colorectal cancer screening test during the intervention year , within the patient population of general practitioners participating in the study and identified as non-up-to-date for their screening status ?
• Identifying potential factors influencing the effectiveness of the intervention based on various characteristics of the patient, the geographical area, the general practitioner, and the caller Researchers will compare with other patients who are not up to date without the intervention of their general practionner with a telephone reminder.

Conditions

Colorectal Cancer Screening

Keywords

prevention; colorectal cancer screening; general practionner

Outcome Measures

Primary Outcomes (1)

• Number of patients who completed the colorectal cancer screening in each arms

  Patients who completed the colorectal cancer screening test during the intervention year (year n), within the patient population of general practitioners participating in the study, and who were identified from the national health insurance list as not up to date with screening - a status that was confirmed by reviewing their medical records. Completion of the screening will be confirmed by the presence of the test result in the patient's medical record within the General practionner's practice software, no later than three months after the end of the intervention. This mesure will be done in each arm.

  6 months after inclusion

Secondary Outcomes (4)

• Percentage of patients whose colorectal cancer screening status was updated according to the National Health Insurance database

  1 year after enrollment

• Number of patients who completed the colorectal cancer screening in the intervention arm according differents variables

  3 months after the end of enrollment

• Number of participants per stage of the intervention process

  3 months after the end of enrollment

• quantifying the time required to carry out the intervention

  3 months after the end of the enrollment

Study Arms (2)

Intervention Arm : phone-based outreach to promote colorectal cancer screening

EXPERIMENTAL

In year n, the 50 selected general practitioners will receive from the national health insurance a list of patients who are not up to date with colorectal cancer screening. Each patient's screening status will be verified by the clinical research associate through a review of the medical records. A telephone call will be made by a member of the patient's primary care team.

Other: Intervention

Control arm

NO INTERVENTION

In year n, the 50 selected general practitioners will receive from the national health insurance a list of patients who are not up to date with colorectal cancer screening. Each patient's screening status will be verified by the clinical research associate through a review of the medical records. There will not be an intervention.

Interventions

Intervention OTHER

A telephone call will be made by a member of the patient's primary care team (general practitioner, medical secretary, public health nurse, or care coordinator), with priority given to a call by the patient's general practitioner. The call should preferably be made to the patient's mobile phone. If the call is unsuccessful, a voicemail message will be left, and a second call will be attempted within the following seven days. The voicemail message will include the name of the patient's general practitioner, the purpose of the call regarding colorectal cancer screening, and notification that a further attempt will be made to reach the patient. If the telephone exchange is successful, an appointment at the healthcare facility will be offered to the patient, during which the screening test will be offered to the patient, during which the screening test will be handed over and explained by one of the healthcare professionals from the same facility.

Intervention Arm : phone-based outreach to promote colorectal cancer screening

Eligibility Criteria

• Age: 50 Years - 74 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Practise in one of the four departments of the Franche-Comté region; ractise in a solo practice, group practice, multidisciplinary primary care centre , or community health centre;
• Are engaged in general medical practice.
• Have agreed to participate in the study.
• patients within the practice population of general practitioners selected to participate in the study;
• aged between 50 and 75 years inclusive;
• affiliated with the French general health insurance scheme or the agricultural social insurance scheme

You may not qualify if:

• practise exclusively in a specialty other than general practice (e.g. osteopathy, allergology, vascular medicine).
• \- Objection expressed by the patient to the change in the purpose of data processing for research purposes

Sponsors & Collaborators

• MSPU des 3 Provinces: lead

Study Sites (1)

MSPU des 3 provinces

Champlitte, Franche-comté, France

Location

MeSH Terms

Interventions

Methods

Intervention Hierarchy (Ancestors)

Investigative Techniques

Central Study Contacts

José-philippe MORENO, MD

CONTACT

+33686663181; jose_philippe.moreno@univ-fcomte.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2025
• First Posted: June 10, 2026
• Study Start (Estimated): December 1, 2026
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): March 1, 2028
• Last Updated: June 10, 2026

Record last verified: 2026-06

Locations

FR (1)