Animated Storytelling to Promote Colorectal Cancer Screening

NCT07522177 | Not Yet Recruiting

• 1 other identifier: 85776
• Study Type: interventional
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

This online randomized controlled trial will evaluate whether a short animated storytelling video increases behavioral expectation to obtain colorectal cancer screening among screening-eligible U.S. adults who report not yet having completed screening. Participants will be recruited via Prolific and randomized in Stanford Qualtrics to view either a brief animated video or a time-neutral informational text. Outcomes will be assessed immediately after exposure.

Conditions

Colorectal Cancer Screening

Outcome Measures

Primary Outcomes (1)

• Change from baseline in behavioral expectation (simple and next-step) to obtain colorectal cancer screening, as measured by a 7-item visual analogue scale.

  Participant self-reports their likelihood of discussing, scheduling, or obtaining colorectal cancer screening after exposure to assigned study material. Total scores range from 0-70 with higher scores indicating greater behavioral expectation (Item 7 is reverse scored).

  Baseline, immediately post-intervention exposure (up to 24 hours)

Secondary Outcomes (2)

• Change from baseline in knowledge about colorectal cancer screening and colonoscopy, as measured by a 5-item knowledge questionnaire.

  Baseline, immediately post-intervention exposure (up to 24 hours)

• Change from baseline in perceptions and beliefs about colonoscopy, as measured by a 13-item scale.

  Baseline, immediately post-intervention exposure (up to 24 hours)

Study Arms (2)

Animated Storytelling Video

EXPERIMENTAL

Participants view a brief animated storytelling video about colorectal cancer screening and colonoscopy.

Behavioral: Short animated storytelling video

Informational Control

ACTIVE COMPARATOR

Participants read a brief time-neutral informational text about colorectal cancer screening.

Behavioral: Informational Text

Interventions

Short animated storytelling video BEHAVIORAL

A brief animated storytelling video about colorectal cancer screening and colonoscopy.

Animated Storytelling Video

Informational Text BEHAVIORAL

A brief time-neutral informational text about colorectal cancer screening.

Informational Control

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Resides in the United States
• Able to read and understand English
• Self-reports not having completed colorectal cancer screening
• Provides electronic informed consent

You may not qualify if:

• Prior diagnosis of colorectal cancer
• Self-reported completion of colorectal cancer screening

Sponsors & Collaborators

• Stanford University: lead
• Heidelberg Institute of Global Health, Heidelberg University, Germany: collaborator

Study Sites (1)

Stanford University

Stanford, California, 94305, United States

Location

Study Officials

• Maya Adam, MD, PhD

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Associate Professor of Pediatrics

Study Record Dates

• First Submitted: April 3, 2026
• First Posted: April 13, 2026
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): August 1, 2026
• Last Updated: April 13, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)