Flow-Controlled Versus Volume-Controlled Ventilation During Suspension Laryngoscopy

NCT07639398 | Completed

• 1 other identifier: 1490/2023
• Study Type: observational
• Target: 71
• Locations: 1 country
• Sites: 1

Brief Summary

Suspension laryngoscopy presents significant challenges for airway management due to the need to maintain adequate ventilation while providing optimal surgical exposure. Flow-controlled ventilation (FCV) is a novel ventilation mode that delivers constant inspiratory and expiratory flow using a narrow-lumen, cuffed endotracheal tube, potentially improving ventilation efficiency in shared-airway surgeries. This prospective observational study aims to compare flow-controlled ventilation and conventional volume-controlled ventilation in patients undergoing elective suspension laryngoscopy. Respiratory mechanics, hemodynamic parameters, perioperative pulmonary function, and procedure-related complications will be evaluated to assess the feasibility and clinical performance of FCV in this surgical setting.

Conditions

Laryngeal Diseases; Airway Management

Keywords

Flow Controlled Ventilation; Volume Controlled Ventilation; Suspension Laryngoscopy; Airway Manegement; Respiratory Mechanics

Outcome Measures

Primary Outcomes (1)

• Peak airway pressure

  Intraoperative peak airway pressure (cmH2O) measured at predefined time intervals during suspension laryngoscopy.

  During surgery with 10 minute intervals

Secondary Outcomes (5)

• Respiratory system compliance

  Intraoperative period during suspension laryngoscopy with 10 minute intervals.

• End tidal carbondioxide

  Intraoperative period during suspension laryngoscopy with 10 minute intervals

• Peripheral oxygen saturation

  Intraoperative period during suspension laryngoscopy with 10 minute intervals.

• Forced expiratory volume in one second

  30 minutes before surgery and 12 hours after surgery

• Forced vital capacity

  30 minutes before surgery and 12 hours after surgery

Study Arms (2)

Flow-Controlled Ventilation Group

Patients undergoing elective suspension laryngoscopy who were ventilated using flow-controlled ventilation based on the attending anesthesiologist's clinical preference.

Volume-Controlled Ventilation Group

Patients undergoing elective suspension laryngoscopy who were ventilated using conventional volume-controlled ventilation based on the attending anesthesiologist's clinical preference.

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18 to 65 years scheduled for elective suspension laryngoscopy under general anesthesia were included. Eligible participants had an American Society of Anesthesiologists (ASA) physical status of I-III and a body mass index between 18 and 40 kg/m². All participants provided written informed consent prior to participation.

You may qualify if:

• American Society of Anesthesiologists (ASA) physical status I-III
• Scheduled for elective suspension laryngoscopy under general anesthesia
• Body mass index between 18 and 40 kg/m²
• Provision of written informed consent

You may not qualify if:

• Inability to cooperate with pulmonary function testing
• Intraoperative hemodynamic instability or oxygen desaturation (SpO₂ \<92%)
• Requirement for tracheostomy during the procedure

Sponsors & Collaborators

• Ankara Training and Research Hospital: lead

Study Sites (1)

Ankara Training and Research Hospital

Ankara, Ankara, 06530, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Laryngeal Diseases

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases; Otorhinolaryngologic Diseases

Study Officials

• Salih Birkan ARI, M.D.

  Ankara Trainig and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.D. Principal investigator

Study Record Dates

• First Submitted: February 3, 2026
• First Posted: June 10, 2026
• Study Start: December 20, 2023
• Primary Completion: February 19, 2024
• Study Completion: February 19, 2024
• Last Updated: June 10, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)