NCT07638657

Brief Summary

The goal of this clinical trial is to find out if autimia, a digital health intervention, can help adults with ASD (Autism Spectrum Disorder) manage their daily lives and improve their well-being. The main questions it aims to answer are:

  • Does autimia, together with regular treatment, improve health outcomes after three months better than regular treatment alone?
  • Are the positive effects of autimia still noticeable after six months? Researchers will compare two groups:
  • Intervention group: Participants use the autimia intervention and continue their usual treatment.
  • Control group: Participants continue with their usual treatment only. Participants will:
  • Participate in a video call with a specialist to confirm a diagnosis of ASD
  • Fill out questionnaires online at the start of the study, after 3 months, and after 6 months
  • Continue with their usual treatment (both groups) and use autimia, a digital health intervention, for six months (intervention group only)

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
236

participants targeted

Target at P75+ for not_applicable

Timeline
11mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 4, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 10, 2026

Completed
20 days until next milestone

Study Start

First participant enrolled

June 30, 2026

Expected
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2027

3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2027

Last Updated

June 12, 2026

Status Verified

June 1, 2026

Enrollment Period

8 months

First QC Date

June 4, 2026

Last Update Submit

June 10, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • 21-item Depression, Anxiety, and Stress Scales (DASS-21) total score

    The DASS-21 is a 21-item PROM to assess psychological distress. The total score is the sum of all items and ranges from 0 to 63. Higher total scores indicate greater psychological distress and thus a worse outcome, whereas lower scores indicate fewer symptoms and a better outcome.

    3 months

Secondary Outcomes (3)

  • Work and Social Adjustment Scale (WSAS) total score

    3 months

  • Social Responsiveness Scale for Adults (SRS-A) total score

    3 months

  • Multidimensional Self Esteem Scale (MSWS) emotional self-esteem subscale score

    3 months

Study Arms (2)

autimia

EXPERIMENTAL

Participants will receive access to the digital health intervention autimia in addition to TAU.

Behavioral: autimia

Control group

NO INTERVENTION

Participants allocated to the control group will receive access to treatment as usual (TAU).

Interventions

autimiaBEHAVIORAL

Participants allocated to the intervention group will receive access to autimia in addition to treatment as usual (TAU). autimia is a digital health intervention designed for individuals with ASD (Autism Spectrum Disorder), accessible through a web browser. The application focuses on treatment methods derived from cognitive behavioral therapy (CBT), health behavior change, and patient education. Topics addressed by autimia are self-acceptance and self-worth, stress management and coping skills, optimizing the environment and communication, as well as understanding emotions and social interactions. The program operates through interactive "dialogues", which are accompanied by illustrations, audio recordings, motivating text messages, worksheets, and summaries. Users are also encouraged to regularly complete short questionnaires to monitor their progress. Once registered, the program remains accessible for six months.

autimia

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • prior suspected diagnosis of ASD by a healthcare professional
  • diagnosis of ASD (ICD-10 codes: F84.5, F84.0, F84.1) confirmed in a semi-structured diagnostic interview conducted as a telemedical consultation
  • IQ ≥ 80
  • increased levels of psychological distress (DASS-21 total score ≥ 21)
  • sufficient knowledge of the German language
  • basic IT skills required for independent use of a digital intervention
  • consent to participation

You may not qualify if:

  • diagnosis of another severe psychiatric disorder (acute severe affective disorder, acute psychotic disorder, acute substance use disorder, borderline personality disorder, antisocial personality disorder)
  • acute suicidality
  • currently being under legal guardianship for healthcare decisions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

GAIA AG

Hamburg, Germany

RECRUITING

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Study Officials

  • Isabel Dziobek, Prof. Dr.

    Humboldt-Universität zu Berlin

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 4, 2026

First Posted

June 10, 2026

Study Start (Estimated)

June 30, 2026

Primary Completion (Estimated)

March 1, 2027

Study Completion (Estimated)

June 1, 2027

Last Updated

June 12, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations