Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children

NCT07636031 | Active Not Recruiting DMC

• 1 other identifier: 09476918.5.0000.0122
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

This study will investigate the feasibility of applying the Rapid Syllable Transition Treatment (ReST) protocol in children with Childhood Apraxia of Speech, considering the scarcity of evidence in the context of Brazilian Portuguese and the need to implement evidence-based interventions in clinical practice. The objective is to evaluate the feasibility of the protocol and estimate preliminary effects on articulatory accuracy, prosody, and speech motor planning. This is a randomized clinical trial with a quantitative and qualitative approach. Participants will be children between five and twelve years old, diagnosed with Childhood Apraxia of Speech. The intervention will be carried out over six weeks, with two weekly sessions, using pseudowords structured according to the ReST protocol. After an initial assessment, participants will be randomized to an intervention group or a control group on a waiting list. Pre- and post-intervention assessments and a one-month follow-up will be conducted. Data analysis will be exploratory, focusing on evaluating the feasibility of the procedures and estimating parameters for future studies. Primary outcomes will include feasibility indicators such as recruitment rate, adherence, therapeutic fidelity, acceptability, and retention. Secondary outcomes will include preliminary measures of speech performance and effect size estimation. The results are expected to provide preliminary effect estimates and inform the design of a definitive randomized clinical trial.

Conditions

Childhood Apraxia of Speech

Keywords

Rapid Sylablle Transition (ReST);; Motor Speech Disorders; Speech Motor Therapy; Childhood apraxia of speech; Speech therapy.

Outcome Measures

Primary Outcomes (1)

• Percentage of correct consonants (PCC)

  Percentage of correctly produced consonants (PCC) for treated and untreated stimuli: Generalization to new words, phrases, sentence contexts, and spontaneous speech; Maintenance of gains in follow-up.

  Assessment performed during follow-up, 4 weeks after the last therapy session.

Study Arms (2)

Rapid Syllable Transition Treatment (ReST) Intervention

EXPERIMENTAL

Speech therapy using the Rapid Syllable Transition Treatment (ReST) intervention method. Indicated for children with Childhood Apraxia of Speech (CAS). Sessions take place twice a week for six weeks (total of 12 sessions), focusing on speech planning and accuracy, using motor learning principles.

Behavioral: Rapid Syllable Transition Treatment (ReST)

control group

NO INTERVENTION

Waiting list, without active intervention during the research, subject to intervention after the research is completed in accordance with ethical terms.

Interventions

Rapid Syllable Transition Treatment (ReST) BEHAVIORAL

Speech-motor therapy based on the Rapid Syllable Transition Treatment (ReST) method, rigorously followed. Its objective is to improve speech motor planning and programming through intensive practice of pseudowords that vary in stress patterns and structure, facilitating training in rapid and precise transitions between syllables.

Rapid Syllable Transition Treatment (ReST) Intervention

Eligibility Criteria

• Age: 5 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Signed informed consent form provided by the child's legal guardians
• Native speakers of Brazilian Portuguese
• Absence of associated comorbidities, verified through detailed clinical history and parent-reported information
• Receptive language abilities superior to expressive language abilities, confirmed through clinical observation and simple comprehension tasks
• Hearing thresholds within normal limits
• Preserved visual acuity
• Age between five and eight years

You may not qualify if:

• Significant cognitive impairments;
• Severe comprehension difficulties that prevent participation in the proposed activities.

Sponsors & Collaborators

• Aline Mara de Oliveira: lead

Study Sites (1)

UFSC

Florianópolis, Santa Catarina, 88085-174, Brazil

Location

MeSH Terms

Conditions

Apraxias; Communication Disorders

Condition Hierarchy (Ancestors)

Psychomotor Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Apenas a pessoa que avaliar os resultados pós-tratamento terá conhecimento da alocação dos grupos.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigador

Study Record Dates

• First Submitted: May 5, 2026
• First Posted: June 9, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): October 1, 2027
• Study Completion (Estimated): January 20, 2028
• Last Updated: June 9, 2026

Record last verified: 2026-06

Locations

BR (1)