NCT06385470

Brief Summary

The proposed study aims to investigate the efficacy of the Dynamic Temporal and Tactile Cueing treatment in Cantonese-English bilingual speakers with childhood apraxia of speech.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
4

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 15, 2024

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

April 22, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 26, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2024

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2025

Completed
Last Updated

April 26, 2024

Status Verified

April 1, 2024

Enrollment Period

4 months

First QC Date

April 22, 2024

Last Update Submit

April 22, 2024

Conditions

Outcome Measures

Primary Outcomes (3)

  • Phonemes accuracy

    Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.

    Change Before, Between, 1-week and 5-week post DTTC treatment

  • Stress accuracy

    Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.

    Change Before, Between, 1-week and 5-week post DTTC treatment

  • Tone accuracy

    Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.

    Change Before, Between, 1-week and 5-week post DTTC treatment

Study Arms (1)

DTTC treatment

EXPERIMENTAL

Four Cantonese-English bilingual children with be randomly assigned to receive either one of the two versions of DTTC (i.e., DTTC in Cantonese \[DTTC-C\] and DTTC in English \[DTTC-E\]) in the first 6-week treatment phase. Then, there will be a 2-week washout period followed by the second 6-week treatment phase with another version of DTTC.

Behavioral: Dynamic Temporal and Tactile Cueing treatment

Interventions

DTTC is a motor-based treatment designed for children with CAS who may have limited verbal output. It applies the principles of motor learning and focuses on speech movement gestures in the context of functional words and phrases. The participants will receive two versions of the DTTC treatment (i.e., DTTC in English \[DTTC-E\] and DTTC in Cantonese \[DTTC-C\]), where probe data will be collected before, during, between and after the treatment intervention.

DTTC treatment

Eligibility Criteria

Age3 Years - 11 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • (1) 3;0 - 11;11 (years;months) years of age at treatment commencement;
  • (2) speak both Cantonese and English: One caregiver one language for at least one year; speaking different languages at home versus school; and/or speak different languages at different times of day;
  • (3) no concomitant developmental disorders including autism spectrum disorder;
  • (4) no structural abnormalities that affect speech, such as cleft lip and/or palate;
  • (5) no uncorrected vision impairment; and
  • (6) no hearing loss;
  • (7) CAS diagnosis confirmed by the research team based on the available diagnostic criteria in Cantonese speakers, which will be described in the next section

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Hong Kong Polytechnic University

Kowloon, Hong Kong

RECRUITING

MeSH Terms

Conditions

Apraxias

Condition Hierarchy (Ancestors)

Psychomotor DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Min Ney Wong, PhD

    Study Principal Investigator

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 22, 2024

First Posted

April 26, 2024

Study Start

April 15, 2024

Primary Completion

August 1, 2024

Study Completion

February 1, 2025

Last Updated

April 26, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will not share

The data sets generated and analyzed during this study are not publicly available due to study institutional review board data security requirements.

Locations