NCT07629414

Brief Summary

This study looks at how people response performing single and dual tasks (cognitive and motor) prior to and after a rapid heat stress that increased core temperature to 39C.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for not_applicable healthy

Timeline
Completed

Started Oct 2024

Typical duration for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 9, 2024

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

May 8, 2026

Completed
28 days until next milestone

First Posted

Study publicly available on registry

June 5, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Completed
Last Updated

June 5, 2026

Status Verified

May 1, 2026

Enrollment Period

1.8 years

First QC Date

May 8, 2026

Last Update Submit

June 4, 2026

Conditions

Outcome Measures

Primary Outcomes (8)

  • expanded timed up and go

    A timed test where participants stand from a chair, walk 10 m, turn, and return to the chair. Longer times indicate slower gait speed

    baseline and post-heat stress, both day 1

  • Firefighter balance test

    A timed test where participants walk an obstacle course measuring dynamic balance, having to step up/down, walk a narrow path, and duck under an obstacle. Longer times indicate worse dynamic balance.

    baseline and post-heat stress, both day 1

  • Backward Digit Recall

    A timed test where participants recall a series of numbers in reverse order. More digits indicate better recall.

    baseline and post-heat stress, both day 1

  • Serial Sevens Subtraction

    A timed test where participants count backwards from a starting value by 7s, with the more correct responses in 20 seconds indicating better cognitive ability for this task.

    baseline and post-heat stress, both day 1

  • Serial Sevens Subtraction-Expanded Timed Up and Go Dual Task

    Performance of serial sevens subtractions while performing the Expanded timed up and go test (ETUG). This test is timed (ETUG) and correct responses tabulated (subtraction).

    baseline and post-heat stress, both day 1

  • Serial Sevens Subtraction-Firefighter Balance Test Dual Task

    Performance of serial sevens subtractions while performing the Firefighter Balance Test (FFBT). This test is timed (FFBT) and correct responses tabulated (subtraction).

    baseline and post-heat stress, both day 1

  • Backward Digit Recall-Expanded Timed Up and Go Dual Task

    Performance of backward digit recall while performing the Expanded timed up and go test (ETUG). This test is timed (ETUG) and correct responses tabulated (Recall).

    baseline and post-heat stress, both day 1

  • Backward Digit Recall-Firefighter Balance Test Dual Task

    Performance of backward digit recall while performing the Firefighter Balance Test (FFBT). This test is timed (FFBT) and correct responses tabulated (Recall).

    baseline and post-heat stress, both day 1

Study Arms (1)

Heat stress

EXPERIMENTAL

Participants will receive the heat stress stimulus

Other: heat stress

Interventions

participants will walk in a heat chamber to increase core temperature

Heat stress

Eligibility Criteria

Age18 Years - 57 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • health via PARQ+

You may not qualify if:

  • inability to safely swallow core temperature pill
  • musculoskeletal injury in past 3 months
  • diagnosed concussion or vestibular disorder
  • known pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

LSU Health Shreveport

Shreveport, Louisiana, 71103, United States

RECRUITING

Related Publications (6)

  • Cheung SS, McLellan TM, Tenaglia S. The thermophysiology of uncompensable heat stress. Physiological manipulations and individual characteristics. Sports Med. 2000 May;29(5):329-59. doi: 10.2165/00007256-200029050-00004.

    PMID: 10840867BACKGROUND
  • Moreira PED, Dieguez GTO, Bredt SDGT, Praca GM. The Acute and Chronic Effects of Dual-Task on the Motor and Cognitive Performances in Athletes: A Systematic Review. Int J Environ Res Public Health. 2021 Feb 10;18(4):1732. doi: 10.3390/ijerph18041732.

    PMID: 33579018BACKGROUND
  • Ness BM, Zimney K, Schweinle WE, Cleland JA. DUAL-TASK ASSESSMENT IMPLICATIONS FOR ANTERIOR CRUCIATE LIGAMENT INJURY: A SYSTEMATIC REVIEW. Int J Sports Phys Ther. 2020 Dec;15(6):840-855. doi: 10.26603/ijspt20200840.

    PMID: 33344002BACKGROUND
  • Ball D. Contrasting effects of heat stress on neuromuscular performance. Exp Physiol. 2021 Dec;106(12):2328-2334. doi: 10.1113/EP088191. Epub 2020 Jul 15.

    PMID: 32608071BACKGROUND
  • Doohan MA, Watzek JT, King N, White MJ, Stewart IB. Does increased core temperature alter cognitive performance during exercise-induced heat strain? A narrative review. J Appl Physiol (1985). 2023 Jul 1;135(1):35-52. doi: 10.1152/japplphysiol.00070.2023. Epub 2023 May 4.

    PMID: 37141422BACKGROUND
  • Donnan K, Williams EL, Morris JL, Stanger N. The effects of exercise at different temperatures on cognitive function: A systematic review. Psychol Sport and Exerc. 2021;54.

    BACKGROUND

MeSH Terms

Conditions

Heat Stress Disorders

Interventions

Heat-Shock Response

Condition Hierarchy (Ancestors)

Wounds and Injuries

Intervention Hierarchy (Ancestors)

Stress, PhysiologicalPhysiological Phenomena

Study Officials

  • Erin McCallister

    Louisiana State University Health Sciences Center Shreveport

    STUDY DIRECTOR

Central Study Contacts

Erin McCallister, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 8, 2026

First Posted

June 5, 2026

Study Start

October 9, 2024

Primary Completion

August 1, 2026

Study Completion

August 1, 2026

Last Updated

June 5, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations