NCT07625813

Brief Summary

This retrospective observational study aims to evaluate early marginal bone loss around dental implants using panoramic radiographs. Radiographic records of patients who underwent mandibular dental implant surgery and implant-supported prosthetic rehabilitation will be reviewed. Marginal bone loss will be measured on the mesial and distal aspects of each implant at final restoration delivery and at follow-up periods after prosthetic loading. The study will also assess patient-, implant-, and prosthesis-related factors associated with marginal bone loss.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
256

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 15, 2025

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 15, 2026

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

May 23, 2026

Completed
12 days until next milestone

First Posted

Study publicly available on registry

June 4, 2026

Completed
Last Updated

June 4, 2026

Status Verified

June 1, 2026

Enrollment Period

1 year

First QC Date

May 23, 2026

Last Update Submit

June 2, 2026

Conditions

Dental ImplantMarginal Bone Loss

Keywords

Dental implantsEarly bone lossMarginal bone lossPeri-implant bone lossImplant-supported prosthesis

Outcome Measures

Primary Outcomes (1)

  • Change in Marginal Bone Loss Over Time

    Marginal bone loss will be assessed on panoramic radiographs by measuring the linear distance from the implant platform to the nearest supporting crestal bone on the mesial and distal aspects of each implant. Mesial, distal, and mean marginal bone loss values will be recorded in millimeters.

    At final restoration delivery, 6 months, 18 months, and 60 months after prosthetic loading

Secondary Outcomes (9)

  • Effect of implant length on mean marginal bone loss

    Up to 60 months after prosthetic loading

  • Effect of implant diameter on mean marginal bone loss

    Up to 60 months after prosthetic loading.

  • Effect of abutment height on mean marginal bone loss

    Up to 60 months after prosthetic loading.

  • Effect of implant-tooth distance on mean marginal bone loss

    Up to 60 months after prosthetic loading.

  • Effect of implant-implant distance on mean marginal bone loss

    Up to 60 months after prosthetic loading.

  • +4 more secondary outcomes

Study Arms (1)

Dental Implant Patients

Patients with mandibular dental implants who had suitable panoramic radiographs for retrospective evaluation of marginal bone loss.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will consist of adult systemically healthy patients who underwent mandibular dental implant surgery and implant-supported prosthetic rehabilitation at Bolu Abant Izzet Baysal University Faculty of Dentistry between 2012 and 2025 and had suitable panoramic radiographs available for retrospective radiographic evaluation of marginal bone loss.

You may qualify if:

  • Individuals older than 18 years
  • Patients with mandibular dental implants
  • Availability of panoramic radiographs obtained after implant surgery and after prosthetic loading
  • Panoramic radiographs suitable for radiographic evaluation
  • Visibility of the mandibular inferior cortex and mental foramen on panoramic radiographs
  • Systemically healthy individuals

You may not qualify if:

  • Low-quality panoramic radiographs
  • Missing follow-up radiographs
  • Presence of systemic diseases or conditions that may affect bone metabolism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Bolu Abant İzzet Baysal University, Department of Periodontics

Bolu, Central, 14100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assist Prof

Study Record Dates

First Submitted

May 23, 2026

First Posted

June 4, 2026

Study Start

January 15, 2025

Primary Completion

January 15, 2026

Study Completion

February 15, 2026

Last Updated

June 4, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)