NCT07625046

Brief Summary

The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours. The study is also done to know if polyphenols will help a hormone called insulin work better in the body, so to look further into the possibility of figs being a functional food for the pre-diabetic population.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for not_applicable

Timeline
11mo left

Started Mar 2026

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress22%
Mar 2026May 2027

Study Start

First participant enrolled

March 12, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 22, 2026

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

May 29, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 4, 2026

Completed
12 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 15, 2027

Expected
Last Updated

June 4, 2026

Status Verified

May 1, 2026

Enrollment Period

2 months

First QC Date

May 29, 2026

Last Update Submit

May 29, 2026

Conditions

Pre Diabetic

Keywords

dried figspre-diabeticPharmacokinetics

Outcome Measures

Primary Outcomes (2)

  • Blood glucose levels

    Blood glucose levels with and without dried figs.

    From enrollment to the end of treatment at 2 weeks

  • Blood Insulin levels

    Blood insulin levels with and without dried figs.

    From enrollment to the end of treatment at 2 weeks

Secondary Outcomes (1)

  • Polyphenols

    From enrollment to the end of treatment at 2 weeks

Study Arms (2)

Fig Breakfast

EXPERIMENTAL

Standardized breakfast with 40g of figs

Other: Fig

Control breakfast

PLACEBO COMPARATOR

Standardized breakfast with calorie matched control ingredients

Other: Control

Interventions

FigOTHER

40g of fig

Fig Breakfast
ControlOTHER

Calorie matched control breakfast

Control breakfast

Eligibility Criteria

Age30 Years - 50 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsFemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Be between 30-50 years old.
  • Have a BMI of 25-35 kg/m².
  • Have fasting blood glucose between 100-125 mg/dL or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
  • Be non-smokers for at least 12 months.
  • Be generally healthy, with no major organ-related diseases.
  • Not take medications or supplements that could interfere with the study.
  • Be able to follow study procedures, including dietary restrictions and scheduled visits

You may not qualify if:

  • Smoker
  • Vegetarian
  • Taking over the counter supplements (e.g. fiber supplements, probiotics and/or prebiotics, antioxidants, anti-inflammation) and/or taking prescription medications that may interfere with study procedures or endpoints (e.g. Gastrointestinal medications, antibiotics) within the last 30 days
  • Have cancer other than non-melanoma skin cancer in previous 5 years
  • Taking unstable dose of hormonal contraceptive and/or stable dose less than 6 months
  • Planning to become pregnant
  • Pregnant and/or breast-feeding
  • Excessive exercisers or trained athletes
  • Excessive coffee/tea drinker
  • Donated blood within last 3 months
  • Have allergies/intolerances to foods consumed in the study
  • Regular consumption of dried fruits exceeds \> 2 servings per day
  • Actively losing weight/ trying to lose weight (unstable body weight fluctuations of \> 5 lbs in 3 months)
  • Addicted to drugs or alcohol or have significant psychiatric or neurological disturbances
  • Past smokers may be allowed in the study if stopped \>2 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Illinois Tech

Chicago, Illinois, 60616, United States

Location

MeSH Terms

Conditions

Glucose Intolerance

Condition Hierarchy (Ancestors)

HyperglycemiaGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Amandeep Sandhu, PHD

    Food Sci and Nut Programs

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 29, 2026

First Posted

June 4, 2026

Study Start

March 12, 2026

Primary Completion

May 22, 2026

Study Completion (Estimated)

May 15, 2027

Last Updated

June 4, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Pilot study

Locations

US(1)