NCT07624981

Brief Summary

Actinic keratoses are precancerous skin lesions that are the most common among all cancers and precancerous conditions in fair-skinned populations. The distinctive feature of these actinic keratoses is that some progress into skin cancers known as cutaneous carcinomas, while others regress spontaneously; currently, there is no way to distinguish between them, either through clinical observation or biological methods. The goal of the Diagno-KA project is to develop a diagnostic test that would distinguish between actinic keratoses that progress to cancer-so they can be surgically removed early (before they become severe and metastasize)-and those that regress, thereby avoiding unnecessary surgical intervention (to prevent scarring).

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
140

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2026

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

May 29, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 3, 2026

Completed
27 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2026

Completed
Last Updated

June 3, 2026

Status Verified

April 1, 2026

Enrollment Period

5 months

First QC Date

May 29, 2026

Last Update Submit

May 29, 2026

Conditions

Skin CancerDiagnostic

Outcome Measures

Primary Outcomes (1)

  • Biomarker validation

    Until the end of the study on average 2 years

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with skin carcinomas and actinic keratoses

You may qualify if:

  • patients with skin carcinomas and actinic keratoses

You may not qualify if:

  • minor patient

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHR Metz-Thionville

Metz, France

Location

MeSH Terms

Conditions

Skin NeoplasmsDisease

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsSkin DiseasesSkin and Connective Tissue DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 29, 2026

First Posted

June 3, 2026

Study Start

February 1, 2026

Primary Completion

June 30, 2026

Study Completion

June 30, 2026

Last Updated

June 3, 2026

Record last verified: 2026-04

Locations

FR(1)