NCT07406022

Brief Summary

Skin carcinomas are the most commonly diagnosed cancers in fair-skinned populations, for example in France, Western Europe, and North America in particular. The OpticSkin project will build and make available to the general public and the scientific and medical community a histological and optical spectroscopic database of healthy, precancerous, and cancerous human skin in terms of absorption, elastic and inelastic scattering (Raman), steady-state and time-resolved autofluorescence, and polarization. The aim is to identify spectroscopic signatures that will be useful for diagnosis.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
140

participants targeted

Target at P50-P75 for all trials

Timeline
45mo left

Started Feb 2026

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress7%
Feb 2026Dec 2029

First Submitted

Initial submission to the registry

January 29, 2026

Completed
3 days until next milestone

Study Start

First participant enrolled

February 1, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

February 12, 2026

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2029

Last Updated

February 12, 2026

Status Verified

January 1, 2026

Enrollment Period

3.9 years

First QC Date

January 29, 2026

Last Update Submit

February 9, 2026

Conditions

Skin CancerDiagnostic

Outcome Measures

Primary Outcomes (1)

  • automated recognition

    automated recognition (by supervised classification) of optical data acquired on different histological classes

    Until the end of the study on average 2 years

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The OpticSkin study will be conducted on paraffin blocks containing skin samples taken from the 140 patients included in the SpectroLive study NCT0295626, ID-RCB: 2016-A00608-43.

You may qualify if:

  • patients with skin carcinomas and actinic keratoses

You may not qualify if:

  • minor patient

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHR Metz-Thionville

Metz, France, 57085, France

Location

MeSH Terms

Conditions

Skin NeoplasmsDisease

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsSkin DiseasesSkin and Connective Tissue DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Andreia CARVALHO DE FREITAS

CONTACT

0033387553323projet-recherche-clinique@chr-metz-thionville.fr

Grégoire Khairallah

CONTACT

g.khairallah@chr-metz-thionville.fr

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 29, 2026

First Posted

February 12, 2026

Study Start

February 1, 2026

Primary Completion (Estimated)

December 31, 2029

Study Completion (Estimated)

December 31, 2029

Last Updated

February 12, 2026

Record last verified: 2026-01

Locations

FR(1)