NCT07624851

Brief Summary

The goal of this clinical trial is to compare one-minute and two-minute compressor rotation intervals during simulated pediatric cardiopulmonary resuscitation, also called CPR. The study will include healthcare professionals who perform chest compressions on a pediatric manikin in a simulated resuscitation setting. The main questions this study aims to answer are: Does one-minute compressor rotation improve chest compression quality compared with two-minute compressor rotation? Does one-minute compressor rotation reduce participant fatigue compared with two-minute compressor rotation? Participants will perform chest compressions during two simulated pediatric CPR sessions. In one session, compressors will rotate every one minute. In the other session, compressors will rotate every two minutes. Researchers will compare CPR performance measures and participant-reported fatigue between the two rotation intervals.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2024

Completed
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2024

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

May 21, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 3, 2026

Completed
Last Updated

June 3, 2026

Status Verified

May 1, 2026

Enrollment Period

29 days

First QC Date

May 21, 2026

Last Update Submit

May 29, 2026

Conditions

Keywords

Pediatric Cardiopulmonary ResuscitationCompressor RotationSimulation TrainingFatigueRandomized Crossover Study

Outcome Measures

Primary Outcomes (3)

  • Chest Compression Rate During Simulated Pediatric CPR

    Chest compression rate was recorded using a manikin-based CPR feedback device during each 20-minute simulated pediatric CPR session. The rate was compared between the one-minute and two-minute compressor rotation conditions.

    From 0 to 20 minutes after the start of each simulated CPR session

  • Chest Recoil Velocity During Simulated Pediatric CPR

    Chest recoil velocity was recorded using a manikin-based CPR feedback device during each 20-minute simulated pediatric CPR session and compared between the one-minute and two-minute compressor rotation conditions.

    From 0 to 20 minutes after the start of each simulated CPR session

  • Proportion of Adequate Chest Compressions

    The proportion of adequate chest compressions was defined as the proportion of compressions meeting the pre-specified rate and depth targets. Adequate compressions were defined as compressions delivered at a rate of 100 to 120 compressions per minute and a target depth of at least 5 cm

    From 0 to 20 minutes after the start of each simulated CPR session

Secondary Outcomes (3)

  • Participant-Reported Fatigue

    At 4, 8, 12, 16, and 20 minutes after the start of each simulated CPR session

  • Blood Pressure Response Before and After Simulated Pediatric CPR

    At baseline and immediately after completion of each simulated CPR session

  • Heart Rate Response During Simulated Pediatric CPR

    At baseline and at 4, 8, 12, 16, and 20 minutes after the start of each simulated CPR session

Study Arms (2)

One-Minute Then Two-Minute Rotation Sequence

EXPERIMENTAL

Participants in this arm first performed simulated pediatric CPR with compressor rotation every one minute. After a rest period, they performed a second simulated pediatric CPR session with compressor rotation every two minutes.

Other: One-Minute Compressor RotationOther: Two-Minute Compressor Rotation

Two-Minute Then One-Minute Rotation Sequence

EXPERIMENTAL

Participants in this arm first performed simulated pediatric CPR with compressor rotation every two minutes. After a rest period, they performed a second simulated pediatric CPR session with compressor rotation every one minute.

Other: One-Minute Compressor RotationOther: Two-Minute Compressor Rotation

Interventions

During simulated pediatric cardiopulmonary resuscitation, chest compressors rotated every one minute. Participants performed chest compressions on a pediatric manikin, and CPR performance metrics were recorded during the simulation.

One-Minute Then Two-Minute Rotation SequenceTwo-Minute Then One-Minute Rotation Sequence

During simulated pediatric cardiopulmonary resuscitation, chest compressors rotated every two minutes. Participants performed chest compressions on a pediatric manikin, and CPR performance metrics were recorded during the simulation.

One-Minute Then Two-Minute Rotation SequenceTwo-Minute Then One-Minute Rotation Sequence

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Volunteer pediatric residents
  • Previous cardiopulmonary resuscitation training
  • Prior clinical cardiopulmonary resuscitation experience
  • Ability to participate in both simulated pediatric CPR sessions
  • Written informed consent provided before study participation

You may not qualify if:

  • No previous Pediatric Advanced Life Support course attendance
  • No prior clinical cardiopulmonary resuscitation experience
  • Currently rotating in the pediatric emergency department or pediatric ward during the study period
  • Emergency medicine residents
  • Presence of a chronic medical condition that could affect physical performance during chest compressions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University

Ankara, Ankara, 06230, Turkey (Türkiye)

Location

Related Publications (4)

  • Sawee C, Churuangsuk C, Vattanavanit V. Effect of Compression Rotation Intervals on Cardiopulmonary Resuscitation Quality: A Systematic Review and Meta-Analysis. Arch Acad Emerg Med. 2025 Jun 25;13(1):e58. doi: 10.22037/aaemj.v13i1.2704. eCollection 2025.

    PMID: 40727595BACKGROUND
  • Kim DH, Seo YW, Jang TC. CPR quality with rotation of every 1 versus 2 minutes as characteristics of rescuers: A randomized crossover simulation study. Medicine (Baltimore). 2023 Mar 10;102(10):e33066. doi: 10.1097/MD.0000000000033066.

    PMID: 36897706BACKGROUND
  • Pechaksorn N, Vattanavanit V. CPR Compression Rotation Every One Minute Versus Two Minutes: A Randomized Cross-Over Manikin Study. Emerg Med Int. 2020 Sep 1;2020:5479209. doi: 10.1155/2020/5479209. eCollection 2020.

    PMID: 32953180BACKGROUND
  • Topjian AA, Raymond TT, Atkins D, Chan M, Duff JP, Joyner BL Jr, Lasa JJ, Lavonas EJ, Levy A, Mahgoub M, Meckler GD, Roberts KE, Sutton RM, Schexnayder SM; Pediatric Basic and Advanced Life Support Collaborators. Part 4: Pediatric Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2020 Oct 20;142(16_suppl_2):S469-S523. doi: 10.1161/CIR.0000000000000901. Epub 2020 Oct 21. No abstract available.

    PMID: 33081526BACKGROUND

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Model Details: Participants completed two simulated pediatric CPR sessions using both compressor rotation strategies. In one session, compressors rotated every one minute, and in the other session, compressors rotated every two minutes. The order of the two strategies was randomized.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator,

Study Record Dates

First Submitted

May 21, 2026

First Posted

June 3, 2026

Study Start

July 1, 2024

Primary Completion

July 30, 2024

Study Completion

September 1, 2024

Last Updated

June 3, 2026

Record last verified: 2026-05

Locations