NCT07621705

Brief Summary

This cluster-randomized waitlist-control trial evaluated Multifamily Healing Spaces (MFHS), a culturally adapted behavioral family intervention for genocide-affected communities in Rwanda. Community members across five districts were screened through a staged triage process. Individuals with acute or severe clinical concerns were routed to clinical referral, those with individual mental-health needs were prioritized for Resilience-Oriented Therapy, and families were invited to MFHS when at least one screened family member met criteria for family communication difficulties. Twenty eligible clusters were randomly selected and then allocated to MFHS or waitlist control. The baseline cohort included 319 family members aged 12 years or older. The trial tested whether MFHS improved family resilience, parenting, couple and youth family-system outcomes, and secondary mental health, psychosocial, community, and livelihood outcomes from baseline to immediate post-intervention endline.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
319

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 28, 2023

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 15, 2023

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

May 20, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 2, 2026

Completed
Last Updated

June 2, 2026

Status Verified

May 1, 2026

Enrollment Period

5 months

First QC Date

May 20, 2026

Last Update Submit

May 29, 2026

Conditions

Keywords

Rwandapost-genocidesocietal healingfamily resiliencefamily systemsmultifamily therapycluster randomized trialintergenerational trauma

Outcome Measures

Primary Outcomes (4)

  • Change in Family Resilience

    Family resilience was measured with the Walsh Family Resilience Questionnaire. The local version included 32 items forming belief systems, organization patterns, and communication/problem solving subscales. Subscale scores range from 1 to 5, with higher scores indicating stronger family resilience processes.

    Baseline to immediate post-intervention endline, up to 5 months

  • Change in Parenting Practices

    Parenting practices were measured with the Parenting Practices Questionnaire. The local version included 20 items forming authoritative warmth/involvement, authoritative democratic participation, and authoritarian verbal hostility subscales. Subscale scores range from 1 to 5, with higher scores indicating more of the named parenting behavior.

    Baseline to immediate post-intervention endline, up to 5 months

  • Change in Parent Couple Functioning

    Parent couple functioning was measured with parent-only measures of dyadic adjustment, dyadic happiness, sexual relationship decision-making power, and preference for boys over girls. Dyadic adjustment domains range from 0 to 3 and dyadic happiness ranges from 1 to 5, with higher scores indicating better couple functioning. Sexual relationship decision-making power ranges from 1 to 3, with higher scores indicating more respondent decision-making authority. Preference for boys over girls ranges from 1 to 4, with higher scores indicating stronger preference for boys over girls.

    Baseline to immediate post-intervention endline, up to 5 months

  • Change in Youth Family-System Functioning

    Youth family-system functioning was measured with youth-only family enmeshment and personal accountability scores. Family enmeshment was measured with seven items ranging from 1 to 5, with higher scores indicating greater over-involvement or lower differentiation. Personal accountability was measured with eight items ranging from 1 to 4, with higher scores indicating greater youth responsibility and accountability.

    Baseline to immediate post-intervention endline, up to 5 months

Secondary Outcomes (6)

  • Change in Post-Traumatic Stress Symptoms

    Baseline to immediate post-intervention endline, up to 5 months.

  • Change in Borderline Traits

    Baseline to immediate post-intervention endline, up to 5 months.

  • Change in Aggression

    Baseline to immediate post-intervention endline, up to 5 months.

  • Change in Forgiveness and Community Relations

    Baseline to immediate post-intervention endline, up to 5 months.

  • Change in Socioemotional Skills

    Baseline to immediate post-intervention endline, up to 5 months.

  • +1 more secondary outcomes

Study Arms (2)

Multifamily Healing Spaces

EXPERIMENTAL

Clusters allocated to Multifamily Healing Spaces (MFHS) received the behavioral family intervention during the trial evaluation period. MFHS was delivered to families in group formats using intergenerational, whole-family, parent-only, and youth-only sessions.

Behavioral: Multifamily Healing Spaces

Waitlist Control

NO INTERVENTION

Clusters allocated to waitlist control did not receive MFHS during the baseline-to-endline evaluation period. Families were invited to receive MFHS after the evaluation period.

Interventions

MFHS is a culturally adapted, group-based family intervention for genocide-affected communities in Rwanda. It includes 18 core 3-hour meeting occasions in intergenerational, whole-family, parent-only, and youth-only formats. Sessions focus on trauma-informed psychoeducation, family communication and problem solving, shared meaning-making, parenting, couple relationships, youth voice, and family and community resilience. Groups were facilitated by trained facilitators, including a therapist and community volunteer, with facilitator training and supervision.

Multifamily Healing Spaces

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Member of a family living in or connected to a selected MFHS-eligible cluster/cell in one of the five study districts in Rwanda.
  • Aged 12 years or older.
  • Family invited because at least one screened family member met the staged MFHS criterion for family communication difficulties after higher-priority clinical and individual mental-health triage.
  • Able and willing to participate in baseline assessment and, if allocated to MFHS, family/group sessions.
  • Written informed consent, assent, and/or caregiver permission obtained according to age and local ethics requirements.

You may not qualify if:

  • Individuals with suicidality, psychosis, or severe substance-use flags were routed for clinical interview or hospital referral rather than MFHS as first-line allocation.
  • Individuals meeting higher-priority individual mental-health criteria were routed to Resilience-Oriented Therapy before the MFHS screening stage.
  • Individuals or families unable to provide consent/assent or safely participate in group family sessions were not enrolled.
  • Remaining individuals with social-conflict indicators after earlier stages were routed to sociotherapy rather than MFHS.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Community and Health-Centre Settings, Ngoma District

Ngoma, Eastern Province, Rwanda

Location

Community and Health-Centre Settings, Nyagatare District

Nyagatare, Eastern Province, Rwanda

Location

Community and Health-Centre Settings, Musanze District

Ruhengeri, Northern Province, Rwanda

Location

Community and Health-Centre Settings, Nyamagabe District

Nyamagabe, Southern Province, Rwanda

Location

Community and Health-Centre Settings, Nyabihu District

Nyabihu, Western Province, Rwanda

Location

Related Publications (2)

  • Lordos, A., Interayamahanga, R., Kayitare, F., Dukuzumuremyi, E., Mahoro, M., Mwiza, J., & Mbanda, J. (2026). Establishing multi-stakeholder alliances to promote societal healing and resilience in post-genocide Rwanda. In S. Clarke-Habibi & C. Reimann (Eds.), The Routledge International Handbook of Trauma-Responsive Peacebuilding (pp. 411-424). Routledge. https://doi.org/10.4324/9781003536970-33

    BACKGROUND
  • Nikolaou, K., Lordos, A., Rutembesa, E., Ioannou, M., Dukuzumuremyi, E., Christou, G., Meade, A., Karayianni, E., Anastasiou, E., Guest, A., Sezibera, V., Panayiotou, O., Throstur, B., & Kayitare, F. (2025). Multifamily Healing Spaces: Development of a family-based intervention for recovery and resilience in Rwanda. Intervention, 23(1), 52-62. https://doi.org/10.4103/intv.intv_16_24

    BACKGROUND

MeSH Terms

Conditions

Psychological TraumaStress Disorders, Post-TraumaticHistorical Trauma

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Officials

  • Alexandros Lordos, PhD

    University of Cyprus

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Baseline enumerators and participants were intended to be unaware of condition assignment during baseline outcome measurement. After allocation, masking could not be assured because local implementation required allocation lists before groups could be convened, and endline masking was difficult to maintain because participants could disclose their allocation status.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Cluster-randomized parallel-group waitlist-control trial. Twenty eligible community/cell clusters were randomly selected from 56 MFHS-eligible cells and then randomly allocated to MFHS or waitlist control. Outcomes were assessed at baseline and immediate post-intervention endline.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Director, Skills and Resilience Lab, Department of Psychology

Study Record Dates

First Submitted

May 20, 2026

First Posted

June 2, 2026

Study Start

April 28, 2023

Primary Completion

September 15, 2023

Study Completion

September 15, 2023

Last Updated

June 2, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will share

De-identified participant-level data underlying the manuscript analyses may be shared with qualified researchers on reasonable request to the first author, subject to ethics, data-protection, and partner-organization approvals.

Shared Documents
STUDY PROTOCOL, SAP, ANALYTIC CODE
Time Frame
Available after publication, with no predetermined end date.
Access Criteria
Researchers must submit a methodologically sound proposal to the first author. Access will be subject to approval by the study team and any applicable ethics, data-protection, and partner-organization requirements. Shared data will be de-identified.

Locations