NCT05275413

Brief Summary

The proposed study is to test the effectiveness of a culturally-attuned, family-based mobile health (mHealth) intervention in reducing symptoms of postnatal depression and promoting health among expectant mothers in Hong Kong. Using a family perspective, the proposed mHealth intervention will engage family members, including expectant fathers and grandparents, in providing support to expectant mothers. Expectant mothers and their family members will be recruited at antenatal clinics at two public hospitals in Hong Kong and randomized to receive the family-based mHealth intervention (experimental), the mother-only mHealth intervention (experimental), or the health education (control). Maternal depression, anxiety and stress, perceived social support, health-related quality of life, and perceived family cohesion will be assessed at recruitment and four weeks after childbirth. For family members, symptoms of anxiety and stress, health-related quality of life, and perceived family cohesion will be measured.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,578

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2022

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 2, 2022

Completed
9 days until next milestone

First Posted

Study publicly available on registry

March 11, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

June 16, 2022

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2023

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

August 22, 2022

Status Verified

August 1, 2022

Enrollment Period

1 year

First QC Date

March 2, 2022

Last Update Submit

August 18, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Postnatal depression symptoms

    Symptoms of maternal depression at four weeks postpartum will be assessed with the validated Chinese version of the 10-item Edinburgh Postnatal Depression Scale (EPDS).

    24 weeks after start of intervention

Secondary Outcomes (4)

  • Perceived social support levels of expectant mothers

    24 weeks after start of intervention

  • Anxiety and stress levels of all participants

    24 weeks after start of intervention

  • Health-related quality of life (QoL) of all participants

    24 weeks after start of intervention

  • Perceived family cohesion levels of all participants

    24 weeks after start of intervention

Study Arms (3)

family-based mHealth intervention

EXPERIMENTAL

The expectant mothers and their family members (fathers and grandparents) in this group will receive health education and support and family support via a smartphone app.

Behavioral: family-based mHealth Intervention

mother-only mHealth intervention

EXPERIMENTAL

The expectant mothers in this group will receive health education and support via a smartphone app.

Behavioral: mother-only mHealth Intervention

Health education

ACTIVE COMPARATOR

The expectant mothers in the control group will receive health education via a smartphone app.

Other: Health education

Interventions

The intervention consists of three versions: mother, father, and grandparent. The app consists of health information about pregnancy, postnatal care, and infant care in the form of brief texts and short videos. Each versions have their unique features, such as a platform to ask questions in mother version, a quiz game to promote fathers' knowledge related to father's involvement, educational materials tailored for grandparents. An obstetrician and a social worker will respond to the questions. Details please refer to the proposal.

family-based mHealth intervention

The expectant mothers in this group will receive information about pregnancy, postnatal care, and infant care in the form of brief texts and short videos via a smartphone app. The expectant mothers will also have access to a platform in the smartphone app to ask questions about their pregnancy. An obstetrician will respond to the questions.

mother-only mHealth intervention

The expectant mothers in the control group will receive information about pregnancy, postnatal care, and infant care in the form of brief texts and short videos via a smartphone app.

Health education

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Expectant mothers (18 years old or above) attending the antenatal clinics at two public hospitals, Kwong Wah Hospital and Tsan Yuk Hospital in Hong Kong and their family members.
  • Possession of a smartphone and a personal email address for receiving and sending information relevant to the study.
  • Willing to accept the study arrangements.

You may not qualify if:

  • Not able to understand written or spoken Chinese.
  • Expectant mothers whose EPDS score is equal to or high than the cut-off score of 10.
  • Not willing or not able to provide informed consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Kwong Wah Hospital

Hong Kong, Hong Kong

RECRUITING

Tsan Yuk Hospital

Hong Kong, Hong Kong

RECRUITING

MeSH Terms

Conditions

Depression, Postpartum

Condition Hierarchy (Ancestors)

Puerperal DisordersPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesDepressive DisorderMood DisordersMental Disorders

Central Study Contacts

Camilla Kin Ming LO, Phd

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 2, 2022

First Posted

March 11, 2022

Study Start

June 16, 2022

Primary Completion

June 30, 2023

Study Completion

December 31, 2023

Last Updated

August 22, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

Locations