NCT07618208

Brief Summary

Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and 2021. This phenomenon particularly affects students, who are already identified as being at greater risk of mental health disorders than the general population. Medical students seem to be particularly vulnerable: in 2021, a national study showed very high rates of depression and suicidal thoughts in this population. The main factor associated with depression was the feeling of financial hardship. Students often face multiple forms of insecurity. Financially, they have limited resources and struggle to cover their basic needs such as housing, food and healthcare. Socially, many experience significant isolation, particularly when they are away from their families or under pressure from their studies. All of this has a significant impact on their mental health. Unfortunately, many students do not seek help due to lack of time, resources, or awareness of support services. The 2021 study showed that only one-third of medical students suffering from depression received appropriate treatment. The aim of our study is to assess the impact of precariousness on the onset of psychiatric disorders and on the use or non-use of healthcare services. Our study will involve nearly 45,000 students from PSL and UPC universities. It is based on a longitudinal cohort (via questionnaires) over three years. The aim is to identify precisely the different aspects of student precariousness (housing, transport, isolation, economic difficulties, etc.) and their link with psychological distress. The study will measure the extent of the phenomenon and identify modifiable factors that could be targeted by preventive measures. The results will enable us to better target preventive measures and propose concrete solutions to improve students' well-being and promote their success.

Trial Health

65
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45,000

participants targeted

Target at P75+ for all trials

Timeline
23mo left

Started Apr 2026

Typical duration for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress10%
Apr 2026Jun 2028

First Submitted

Initial submission to the registry

March 4, 2026

Completed
28 days until next milestone

Study Start

First participant enrolled

April 1, 2026

Completed
2 months until next milestone

First Posted

Study publicly available on registry

June 1, 2026

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2028

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Last Updated

June 1, 2026

Status Verified

March 1, 2026

Enrollment Period

2 years

First QC Date

March 4, 2026

Last Update Submit

May 26, 2026

Conditions

Keywords

StudentsDepressionUse of carePrecarity

Outcome Measures

Primary Outcomes (6)

  • Composite International Diagnostic Interview Short-Form (CIDI-SF)

    12-months prevalence Major Depressive Disorder and suicidal thoughts Composite International Diagnostic Interview Short-Form (CIDI-SF)

    Day 0

  • Composite International Diagnostic Interview Short-Form (CIDI-SF)

    12-months prevalence Major Depressive Disorder and suicidal thoughts Composite International Diagnostic Interview Short-Form (CIDI-SF)

    12 months

  • Use of care

    Use of care service of care professional

    Day 0

  • Use of care

    Use of care service of care professional

    12 months

  • Precarity

    Question "Would you say that you are currently experiencing financial difficulties?"

    Day 0

  • Precarity

    Question "Would you say that you are currently experiencing financial difficulties?"

    12 months

Secondary Outcomes (37)

  • GAD7

    Day 0

  • GAD7

    12 months

  • GAD7

    24 months

  • SCOFF

    Day 0

  • SCOFF

    12 months

  • +32 more secondary outcomes

Study Arms (2)

Health students

All students enrolled at the Faculty of Health Sciences of Paris Cité University

Other: Questionnaires

Non-health students

All students enrolled at Paris Sciences and Letters University

Other: Questionnaires

Interventions

Questionnaires

Health studentsNon-health students

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All students enrolled at Paris Sciences et Lettres University or the Faculty of Health Sciences at Paris Cité University.

You may qualify if:

  • Student enrolled at Paris Sciences et Lettres University (PSL, 17,000 students) or the Faculty of Health Sciences at Paris Cité University (UPC, 28,000 students),
  • Aged 18 or over,
  • Fluent in French,
  • Affiliated to a health insurance.

You may not qualify if:

  • Applicants under the age of 18,
  • Not enrolled at PSL universities or the UPCS Faculty of Health,
  • Insufficient level of French.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Depressive Disorder, MajorGeneralized Anxiety DisorderSuicidal IdeationDepression

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Depressive DisorderMood DisordersMental DisordersAnxiety DisordersSuicideSelf-Injurious BehaviorBehavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Central Study Contacts

Cédric LEMOGNE, PR

CONTACT

Marie Benhammani-Godard

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 4, 2026

First Posted

June 1, 2026

Study Start

April 1, 2026

Primary Completion (Estimated)

April 1, 2028

Study Completion (Estimated)

June 1, 2028

Last Updated

June 1, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share