NCT07615257

Brief Summary

Your research study is about evaluating the effectiveness of \*\*Mindfulness-Based Cognitive Therapy (MBCT)\*\* in reducing psychological distress among psoriasis patients and improving their self-compassion and Mental Health Locus of Control (MHLC). The study highlights that psoriasis patients often suffer not only from physical symptoms but also from psychological problems such as stress, anxiety, depression, self-judgment, and low self-compassion. Traditional treatments mainly focus on physical symptoms and may not fully address these emotional and psychological difficulties. To address this gap, the study proposes MBCT as a psychological intervention that combines mindfulness practices with cognitive therapy techniques. MBCT helps patients become more self-aware, reduce negative thinking, and develop self-compassion without self-judgment. The research also explores MHLC, which refers to how much control individuals believe they have over their health outcomes. The study aims to investigate whether MBCT can:

  • Reduce psychological distress, anxiety, depression, and stress levels
  • Improve self-compassion among psoriasis patients
  • Shift patients' locus of control from external to internal
  • Enhance emotional well-being and coping mechanisms The research follows a quantitative experimental design conducted in phases. Initially, baseline levels of distress, MHLC, and self-compassion will be assessed. Later, MBCT interventions will be implemented and evaluated for effectiveness. Overall, the study seeks to contribute to integrated psoriasis care by emphasizing the importance of psychological health alongside physical treatment, ultimately improving patients' quality of life and therapeutic outcomes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
128

participants targeted

Target at P50-P75 for not_applicable

Timeline
6mo left

Started Feb 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress73%
Feb 2025Dec 2026

Study Start

First participant enrolled

February 5, 2025

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

May 22, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 29, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 12, 2026

Last Updated

May 29, 2026

Status Verified

May 1, 2026

Enrollment Period

1.7 years

First QC Date

May 22, 2026

Last Update Submit

May 22, 2026

Conditions

Psoriasis

Outcome Measures

Primary Outcomes (1)

  • Reduction in Psychological Distress

    To evaluate the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in reducing psychological distress among psoriasis patients.

    12 weeks

Study Arms (2)

Experimental Group

EXPERIMENTAL

Participants in this group will receive Mindfulness-Based Cognitive Therapy (MBCT) intervention.

Behavioral: Mindfulness-Based Cognitive Therapy (MBCT)

Control Group

EXPERIMENTAL

Participants in this group will receive usual care without MBCT intervention.

Other: Usual Care

Interventions

Mindfulness-Based Cognitive Therapy (MBCT)BEHAVIORAL

Mindfulness-Based Cognitive Therapy (MBCT) will be administered to psoriasis patients to reduce psychological distress and improve self-compassion and mental health locus of control. The intervention includes mindfulness practices and cognitive behavioral techniques delivered in structured sessions.

Experimental Group
Usual CareOTHER

Participants in the control group will receive usual care without Mindfulness-Based Cognitive Therapy intervention.

Control Group

Eligibility Criteria

Age25 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed psoriasis patients
  • Age between 18 and 65 years
  • Both male and female participants
  • Participants willing to provide informed consent
  • Participants experiencing psychological distress

You may not qualify if:

  • Under the age of 18 years will be excluded.
  • Patients with severe psychiatric disorders
  • Patients currently receiving other psychological therapies
  • Patients with serious medical or neurological conditions
  • Participants unwilling to continue the intervention sessions
  • Patients with cognitive impairment affecting participation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Dermatologist Sheikh Zayed Hospital Rahim Yar Khan

Rahim Yar Khan, Punjab Province, 64200, Pakistan

RECRUITING

MeSH Terms

Conditions

Psoriasis

Interventions

Mindfulness-Based Cognitive Therapy

Condition Hierarchy (Ancestors)

Skin Diseases, PapulosquamousSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

MindfulnessCognitive Behavioral TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Central Study Contacts

Rafia Ghaffar, Phd

CONTACT

923336096376rafiaghaffar1@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD scholar

Study Record Dates

First Submitted

May 22, 2026

First Posted

May 29, 2026

Study Start

February 5, 2025

Primary Completion (Estimated)

November 1, 2026

Study Completion (Estimated)

December 12, 2026

Last Updated

May 29, 2026

Record last verified: 2026-05

Locations

PA(1)