Assessment of the Effect of a Dermatology-Oriented Spa Therapy on the Quality of Life of Patients With Psoriasis

NCT06735911 | Recruiting

• 1 other identifier: 2024-A00700-47
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 2

Brief Summary

Evaluation of the effect of a dermatology-oriented spa therapy at 4.5 months on the quality of life of patients suffering from psoriasis

Conditions

Psoriasis

Keywords

psoriasis; spa therapy

Outcome Measures

Primary Outcomes (1)

• To evaluate the effect of a complete thermal treatment (moderate impact) for a dermatological indication on the quality of life of patients with psoriasis

  Percentage of patients with a score ≤ 10 (moderate impact) on the Dermatology Life Quality Index (DLQI) questionnaire at 4.5 months.The DLQI score is between 0 and 30 where a high score indicates a significant impairment of quality of life.

  4.5 months

Secondary Outcomes (13)

• To evaluate the effect of a complete thermal treatment (low impact) for a dermatological indication on the quality of life of patients with psoriasis at 4.5 months, taking into account all the care provided

  4.5 months

• To evaluate dermatology-specific quality of life (quantitative DLQI score)

  4.5 and 9 months

• To evaluate overall quality of life using the EQ-5D-5L questionnaire.

  4.5 and 9 months

• To evaluate the clinical improvement of psoriasis in the short and medium term.

  4.5 and 9 months

• To evaluate pain and pruritus.

  4.5 and 9 months

Study Arms (1)

Experimental: patient treated with a dermatology-oriented spa therapy

EXPERIMENTAL

Thermal treatments among the following: Filiform shower, simple bath, aerated bath, general shower, compresses, nebulization inhalation, multiple local mud applications, and drinking cure.

Other: Spa therapy

Interventions

Spa therapy OTHER

Thermal treatments among the following: Filiform shower, simple bath, aerated bath, general shower, compresses, nebulization inhalation, multiple local mud applications, and drinking cure.

Also known as: spa treatment, spa care

Experimental: patient treated with a dermatology-oriented spa therapy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years Patient with psoriasis Stable treatment in the last 6 months. DLQI \> 10 Patient presenting an indication for thermal treatment focused on dermatology (possible dual orientation).
• Patient affiliated to the social security system or such a system Available for an 18-day spa treatment and a 9-month follow-up For women of childbearing age: effective contraception Patient information and informed consent signature

You may not qualify if:

• Contraindication to thermal treatment (e.g., ongoing chemotherapy/radiotherapy, uncontrolled progressive neoplasia, progressive heart disease, etc., according to the investigator's assessment) Predictable intolerance to thermal treatments (intolerance to heat, baths, etc.) Patient who has already undergone a dermatology-oriented spa treatment within the current thermal season Subject already included in an interventional clinical research protocol Persons referred to in articles L1121-5 to L1121-8 of the "Code de la Santé Publique" (pregnant women, women in labour and parturient and nursing mothers, persons deprived of liberty by judicial or administrative decision, persons subject to a legal protection measure or not being able to verbally communicate their agreement, minor)

Sponsors & Collaborators

• Thermes de Bareges: lead
• Floralis: collaborator
• University Grenoble Alps: collaborator

Study Sites (2)

Centre Hospitalier Victor Dupouy

Argenteuil, 95107, France

RECRUITING

Cabinet Luz Saint Sauveur

Pierrefitte-Nestalas, 65120, France

RECRUITING

Related Publications (3)

• Lebwohl M, Ellis C, Gottlieb A, Koo J, Krueger G, Linden K, Shupack J, Weinstein G. Cyclosporine consensus conference: with emphasis on the treatment of psoriasis. J Am Acad Dermatol. 1998 Sep;39(3):464-75. doi: 10.1016/s0190-9622(98)70325-1.

  PMID: 9738783 BACKGROUND

• SOLOMON WM, NETHERTON EW, NELSON PA, ZEITER WJ. Treatment of psoriasis with Goeckerman technic. Arch Phys Med Rehabil. 1955 Feb;36(2):74-7. No abstract available.

  PMID: 13229486 BACKGROUND

• Kazandjieva J, Grozdev I, Darlenski R, Tsankov N. Climatotherapy of psoriasis. Clin Dermatol. 2008 Sep-Oct;26(5):477-85. doi: 10.1016/j.clindermatol.2008.05.001.

  PMID: 18755366 BACKGROUND

MeSH Terms

Conditions

Psoriasis

Condition Hierarchy (Ancestors)

Skin Diseases, Papulosquamous; Skin Diseases; Skin and Connective Tissue Diseases

Central Study Contacts

FUSTIER NF Nans

CONTACT

04 76 76 50 40; nans.fustier@univ-grenoble-alpes.fr

ROLLAND CR Carole

CONTACT

04 76 76 50 40; carole.rolland@univ-grenoble-alpes.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: before / after study

Study Record Dates

• First Submitted: December 11, 2024
• First Posted: December 16, 2024
• Study Start: April 28, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): May 1, 2028
• Last Updated: May 13, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (2)