NCT07610785

Brief Summary

The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors. The main questions it aims to answer are:

  • Can implementing specific music to listen to for 20 minutes a day for 25 days improve suicidality?
  • Can implementing education around the psychology of the medicine of music improve mental health outcomes? Participants will:
  • Listen to music given to them by the study team for 20 minutes a day for 25 days
  • Receive musical psychoeducation on how to improve mood using music

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
9mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress19%
Jun 2026May 2027

First Submitted

Initial submission to the registry

May 20, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 28, 2026

Completed
4 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2027

Last Updated

May 28, 2026

Status Verified

May 1, 2026

Enrollment Period

11 months

First QC Date

May 20, 2026

Last Update Submit

May 20, 2026

Conditions

Suicidal Thoughts and Behaviors

Keywords

SuicidalityMusic-based interventionMusic

Outcome Measures

Primary Outcomes (3)

  • Change in Suicidality via Beck Scale for Suicidal Ideation (BSS/BSSI) Score

    A 19-item scale with each item scoring from 0-2 rating an individual's suicidal thoughts, intent, and ideation. The total score ranges from 0 to 38. A higher score indicates more intense suicidal ideation and a low score indicates less intense suicidal ideation.

    Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).

  • Change in Generalized Anxiety Disorder Status via Generalized Anxiety Disorder-7 (GAD-7) Score

    A 7-item measure scaled 0-3 per item that measures symptoms of Generalized Anxiety Disorder. 0 would be no sign of anxiety and 3 would indicate high level of anxiety over the last two weeks.

    Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).

  • Change in Depression Status via Patient Health Questionnaire-9 (PHQ-9) Score

    A 9-item questionnaire that measures symptoms of depression on a 0-3 scale over the last two weeks. 0 would indicate "not at all", 1 would indicate "several days", 2 would indicate "most of the days", and a 3 would indicate "nearly every day".

    Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).

Secondary Outcomes (3)

  • Change in Music Listening Purpose via Healthy-Unhealthy Music Scale (HUMS) - Healthy Score

    Baseline, end of study (up to 25 days).

  • Change in Music Listening Purpose via Healthy-Unhealthy Music Scale (HUMS) - Unhealthy Score

    Baseline, end of study (up to 25 days).

  • Acceptability Scale Score

    At the end of the intervention (25 days after enrollment).

Study Arms (1)

STAMM-S

EXPERIMENTAL

Participants receive musical psychoeducation and take a dose of 20 minutes of adaptive music per day for 25 days.

Behavioral: STAMM-S

Interventions

STAMM-SBEHAVIORAL

Participants will undergo the STAMM-S treatment, which involves music generated using machine learning to move to a more positive affect. They will also receive education on how to best use the music assigned to improve their mood.

STAMM-S

Eligibility Criteria

Age14 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age 14-35 years
  • Suicidal ideation (C-SSRS categories 1-3 within the past month)
  • normal sensitivity to music reward on the Barcelona Music Reward Questionnaire. Score \>65

You may not qualify if:

  • imminent or acute suicide risk (C-SSRS categories 4-5).
  • Co-morbid substance use disorder.
  • Co-morbid psychotic disorder.
  • current participation in another trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yuukis Hall - Stanford University

Palo Alto, California, 94304, United States

Location

MeSH Terms

Conditions

Suicidal IdeationBehavior

Condition Hierarchy (Ancestors)

SuicideSelf-Injurious BehaviorBehavioral Symptoms

Study Officials

  • Daniel L. Bowling, PhD

    Stanford University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Sciences)

Study Record Dates

First Submitted

May 20, 2026

First Posted

May 28, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

May 1, 2027

Study Completion (Estimated)

May 1, 2027

Last Updated

May 28, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations

US(1)