NCT07609511

Brief Summary

Evaluate the performance and safety of the GT Metabolic Magnet System to create side-to-side gastroenteral magnetic compression anastomosis (gastroenterostomy).

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
4mo left

Started Jul 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress21%
Jul 2026Dec 2026

First Submitted

Initial submission to the registry

May 18, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 27, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

July 1, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

May 27, 2026

Status Verified

May 1, 2026

Enrollment Period

5 months

First QC Date

May 18, 2026

Last Update Submit

May 21, 2026

Conditions

Keywords

Magnet SystemGT Metabolic Solutions, Inc.

Outcome Measures

Primary Outcomes (2)

  • Natural Magnet Passage

    Successful passage of magnets without invasive reintervention

    90 days

  • Anastomosis Patency

    Creation of a patent anastomosis (confirmed by gastroscopy / endoscopy)

    90 days

Study Arms (1)

Magnet System

EXPERIMENTAL

GT Metabolic Magnet System comprised of GT Metabolic Magnet System ("Magnet System")

Device: Magnet System

Interventions

Magnetic compression, side-to-side anastomosis, in patients with Gastric Outlet Obstruction and indicated for a gastroenterostomy

Magnet System

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Gastric outlet obstruction (GOO) and indicated for a gastroenterostomy, per the discretion of the treating investigator.
  • If a child-bearing female, subject must commit to not becoming pregnant and agree to use contraception for the duration of the study.
  • Willing and able to comply with protocol requirements and provides written informed consent to participate in the study.

You may not qualify if:

  • Prior surgery, trauma, prostheses, disease or genetic expression which prevent or contraindicate the gastroenterostomy procedure.
  • If GOO due to malignant neoplasm:
  • Baseline Eastern Cooperative Oncology Group (ECOG) \> 2 and/or Karnofsky Performance score \< 30
  • Gastric or intestinal cancer or malignant infiltration precluding creation of a magnetic compression anastomosis (per investigator discretion)
  • Coagulation disorders, on continuous or complete anticoagulation, or other conditions associated with high risk of bleeding and not correctable or manageable, precluding creation of a magnetic compression anastomosis (per investigator discretion)
  • Any anomaly precluding orogastric access by endoscope and catheters, and manipulation techniques.
  • Implantable pacemaker or defibrillator.
  • Woman who is either pregnant or breast feeding.
  • Any comorbidity or current status of subject's physiological fitness that in the surgeon's or anesthesiologist's opinion represents safety concerns that make the subject medically unfit for the procedure, including any significant congenital or acquired anomalies of the GI tract at or distal to the placement of the Magnets.
  • Unhealed ulcers, bleeding lesions, tumor, or any other lesion at target Magnet deployment sites.
  • Expected need for Magnetic Resonance Imaging (MRI) within the first 2 months after the procedure.
  • Any anomaly preventing/contraindicating endoscopic or laparoscopic access and procedures.
  • Active infections requiring antibiotic therapy, unless resolved before undergoing the study procedure.
  • Unable to comply with the follow-up schedule and assessments.
  • Known allergies to the device components or contrast media.
  • +2 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

General University Hospital

Prague, Czechia

Location

MeSH Terms

Conditions

Gastric Outlet Obstruction

Condition Hierarchy (Ancestors)

Stomach DiseasesGastrointestinal DiseasesDigestive System Diseases

Central Study Contacts

Lisa Griffin Vincent, PhD, MA

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 18, 2026

First Posted

May 27, 2026

Study Start

July 1, 2026

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

May 27, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations