3A-OR Very Brief Tobacco Cessation Intervention in Primary Care
The Effectiveness of the 3A-OR Very Brief Tobacco Cessation Intervention in Primary Care: A Multicenter Pragmatic Trial Protocol
1 other identifier
interventional
2,400
1 country
1
Brief Summary
Introduction: Türkiye is far from the World Health Organization (WHO)'s target of reducing tobacco use prevalence by 30% by 2025. Most tobacco users consider quitting, and most have attempted to quit at least once. However, the success rate of quitting on one's own is quite low. Studies demonstrating that very brief tobacco cessation interventions delivered by healthcare professionals increase cessation rates have almost entirely been conducted in hospital settings. The aim of this trial is to investigate the effectiveness of implementing the 3A-OR (Ask - Assess - Advise - Offer Assistance - Record) very brief tobacco cessation intervention in routine primary care family medicine practice on the success of tobacco cessation. Methods/design: This protocol describes a two-arm, multicenter pragmatic trial for adolescent and adult tobacco users. The project will be carried out in family health centers in 21 study sites across the 12 statistical regions of Türkiye. In the intervention arm, volunteer family physicians will implement the 3A-OR very brief tobacco cessation intervention to their patients as part of their routine clinical practice. The intervention consists of the following steps: 'asking patients about their tobacco use status', 'assessing users' motivation to quit', 'advising quitting based on their motivation status', 'offering cessation assistance', and 'recording information regarding patients' tobacco use status and repeating the intervention at each patient contact'. Routine practice in family health centers will constitute the control group. Data will be collected using standard questionnaire forms at baseline and during follow-up interviews at 3, 6, and 12 months. Tobacco cessation rate and increase in smokers' motivation were the primary outcomes of the trial. Discussion: If the 3A-OR very brief tobacco cessation intervention is found to be effective, the results of this trial will provide evidence that will encourage the widespread use of the intervention in primary care family health centers. The study results are intended to be disseminated through the Family Medicine Academy Association website, conference presentations, and scientific publications.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2026
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 28, 2026
CompletedFirst Posted
Study publicly available on registry
May 27, 2026
CompletedStudy Start
First participant enrolled
June 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 30, 2027
May 27, 2026
May 1, 2026
2 months
April 28, 2026
May 21, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Smoking cessation success
Patient-reported success in quitting tobacco use among smokers in the intervention and control groups at the end of three, six, and twelve months
At 3, 6 and 12-month follow ups
Secondary Outcomes (1)
Motivational change
At 3, 6 and 12-month follow ups
Study Arms (2)
Study Group
ACTIVE COMPARATORparticipants who used tobacco products and underwent the intervention
Control Group
NO INTERVENTIONParticipants who use tobacco products but were not subjected to the intervention, usual care
Interventions
The intervention consists of the following steps: 'asking patients about their tobacco use status', 'assessing users' motivation to quit', 'advising quitting based on their motivation status', 'offering cessation assistance', and 'recording information regarding patients' tobacco use status and repeating the intervention at each patient contact'.
Eligibility Criteria
You may qualify if:
- Being aged 15 years and older (including pregnant and breastfeeding women);
- Having used any tobacco product at least once daily within the last month;
- All smokers, regardless of their intention to quit tobacco use;
- Providing a phone number for follow-up;
- Being able to read and speak Turkish;
- Signing the informed consent form.
You may not qualify if:
- Using tobacco products less than once per day;
- Having made an attempt to quit tobacco use within the last month;
- Having impaired cognitive functions;
- Having participated in another study on tobacco use within the past year.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Family Health Centers
Aydin, Turkey (Türkiye)
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Melda Dibek, MD
Adnan Menders University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, CARE PROVIDER
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
April 28, 2026
First Posted
May 27, 2026
Study Start
June 1, 2026
Primary Completion (Estimated)
July 31, 2026
Study Completion (Estimated)
June 30, 2027
Last Updated
May 27, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will not share