Influence of Tea Consumption on Human Glycemic Response
1 other identifier
interventional
20
1 country
1
Brief Summary
The specific aim of this study is to evaluate the postprandial metabolic responses of individuals to tea varieties when consumed individually or together with a standardized meal.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Mar 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 19, 2026
CompletedStudy Start
First participant enrolled
March 25, 2026
CompletedFirst Posted
Study publicly available on registry
May 27, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2027
May 27, 2026
February 1, 2026
8 months
February 19, 2026
May 19, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Changes in laboratory analysis of blood glucose and insulin measurements at 9 timepoints over 3 hours for each session
Approximately 16 weeks from enrolment to the end of study
Study Arms (5)
Tea Type #1
EXPERIMENTALIn this intervention, participants will be cannulated and required to consume a specific tea beverage #1. Blood will be drawn through the cannula at 9 different timepoints (0, 15, 30, 45, 60, 90, 120, 150, 180 min) to test for glucose, insulin, lipids, and other metabolic biomarkers.
Tea Type #2
EXPERIMENTALIn this intervention, participants will be cannulated and required to consume a specific tea beverage #2. Blood will be drawn through the cannula at 9 different timepoints (0, 15, 30, 45, 60, 90, 120, 150, 180 min) to test for glucose, insulin, lipids, and other metabolic biomarkers.
Tea Type #1 + Standardized Meal
EXPERIMENTALIn this intervention, participants will be cannulated and required to consume a specific tea beverage #1 and a standardized meal. Blood will be drawn through the cannula at 9 different timepoints (0, 15, 30, 45, 60, 90, 120, 150, 180 min) to test for glucose, insulin, lipids, and other metabolic biomarkers.
Tea Type #2 + Standardized Meal
EXPERIMENTALIn this intervention, participants will be cannulated and required to consume a specific tea beverage #2 and a standardized meal. Blood will be drawn through the cannula at 9 different timepoints (0, 15, 30, 45, 60, 90, 120, 150, 180 min) to test for glucose, insulin, lipids, and other metabolic biomarkers.
Standardized Meal
EXPERIMENTALIn this intervention, participants will be cannulated and required to consume a standardized meal. Blood will be drawn through the cannula at 9 different timepoints (0, 15, 30, 45, 60, 90, 120, 150, 180 min) to test for glucose, insulin, lipids, and other metabolic biomarkers.
Interventions
This is a specific tea variety #1 that will be consumed by participants. It contains milk, a small amount of sugar, and will be served cold with ice.
This is a specific tea variety #1 that will be consumed by participants. It contains milk, a small amount of sugar, and will be served cold with ice.
This is a ready to eat meal that can be purchased off the shelves in local stores. The same meal is used for several study arms to serve as a standardization on the nutritional content consumed.
Eligibility Criteria
You may qualify if:
- Male
- Chinese ethnicity
- Ages 21-60 years old (inclusive)
- Healthy
- Weigh at least 50kg
- Must be English-literate and able to give informed consent in English
- Reliable and willing to make themselves available for the duration of the study and are willing to follow study procedures
You may not qualify if:
- Female
- A current smoker, or has smoked in the past 2 years
- Fasting glucose \>= 7 mmol/L
- History of type 1/type 2 diabetes
- Regular use of medication that may affect glucose metabolism (e.g., steroids)
- Being diagnosed with cancer, heart disease, stroke, renal failure, serious mental or physical illnesses at the time of recruitment
- History of food allergies to test products (milk tea) i.e. milk allergies, or lactose intolerance
- History of food allergies to any of the ready made meals (such as soy, peanuts, eggs, shellfish etc)
- Have donated blood of more than 500 mL within 8 weeks of study enrolment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- National University of Singaporelead
- Tea Explorer Pte. Ltd.collaborator
Study Sites (1)
National University of Singapore, Department of Food Science & Technology
Singapore, Singapore
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mei Hui Liu, PhD
National University of Singapore
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr Liu Mei Hui, Senior Lecturer, Department of Food Science & Technology
Study Record Dates
First Submitted
February 19, 2026
First Posted
May 27, 2026
Study Start
March 25, 2026
Primary Completion (Estimated)
December 1, 2026
Study Completion (Estimated)
June 1, 2027
Last Updated
May 27, 2026
Record last verified: 2026-02