The Effects of Exercise on Glycaemic Response of Low or High Glycaemic Index Meals

NCT03484858 | Completed

• 1 other identifier: 2015/01092
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the current study is to determine the effect of sprint interval training (SIT) in conjunction with either high or low glycaemic index meals (breakfast, lunch and dinner) on the 24-hour glycaemic profile and glucoregulatory hormones in Asian males.

Conditions

Glycaemic Response

Outcome Measures

Primary Outcomes (2)

• Glycaemic response

  Measured using continuous glucose monitoring system

  up to 24 hours

• Glycaemic response

  Venous blood obtained through cannula, analysed using COBAS Analyzer

  up to 8 hours

Secondary Outcomes (2)

• Blood biochemistry

  up to 8 hours

• Hunger and satiety

  up to 8 hours

Study Arms (4)

High glycaemic index meal and exercise

OTHER

Other: High glycaemic index meal and exercise

High glycaemic index meal and rest

OTHER

Other: High glycaemic index meal and rest

Low glycaemic index meal and exercise

OTHER

Other: Low glycaemic index meal and exercise

Low glycaemic index meal and rest

OTHER

Other: Low glycaemic index meal and rest

Interventions

High glycaemic index meal and exercise OTHER

High glycaemic index meal and exercise

High glycaemic index meal and rest OTHER

High glycaemic index meal and rest

Low glycaemic index meal and exercise OTHER

Low glycaemic index meal and exercise

Low glycaemic index meal and rest OTHER

Low glycaemic index meal and rest

Eligibility Criteria

• Age: 21 Years - 40 Years
• Gender Eligibility Details: Healthy male voluteers
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male
• Age between 21-40 years
• Chinese Ethnicity
• Body mass index between 17 - 25 kg m2
• Fasting blood glucose (\< 6 mmol/L)
• Normal blood pressure (\< 140/90 mmHg)
• Do not have metabolic diseases (such as diabetes, hypertension etc.)
• Do not have glucose-6-phosphate dehydrogenase (G6PD) deficiency
• Do not take prescription medication that may affect metabolism
• Low activity level (≤ 60 min of moderate-intensity exercise weekly)
• Do not intentionally restrict food intake
• Do not have intolerances or allergies to test foods

Sponsors & Collaborators

• Singapore Institute of Food and Biotechnology Innovation: lead

Study Sites (1)

Clinical Nutrition Research Centre

Singapore, 117599, Singapore

Location

MeSH Terms

Interventions

Exercise; RE1-silencing transcription factor

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Randomized cross over design

Study Record Dates

• First Submitted: March 26, 2018
• First Posted: April 2, 2018
• Study Start: December 17, 2015
• Primary Completion: March 1, 2018
• Study Completion: March 1, 2018
• Last Updated: April 2, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share

Locations

SG (1)