NCT07608653

Brief Summary

The goal of this clinical trial is to learn if a laparoscopic surgery called Transabdominal Preperitoneal (TAPP) repair is safe and works well for adults with a recurrent inguinal hernia (a groin hernia that has returned after a previous operation). The main questions it aims to answer are: Does the TAPP technique lower the number of complications after surgery? How well do participants recover during the early postoperative period and long-term follow-up? Fixing a hernia that has returned is hard because of old scar tissue. In this study, researchers will use the TAPP technique to work through a different layer of tissue to provide a stronger repair. Participants will: Undergo the TAPP laparoscopic surgery for their recurrent hernia. Visit the clinic for close health monitoring shortly after surgery. Complete regular follow-up checkups to track their long-term recovery.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
0mo left

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress83%
Apr 2026Jul 2026

Study Start

First participant enrolled

April 1, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 20, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 27, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2026

Last Updated

June 1, 2026

Status Verified

May 1, 2026

Enrollment Period

3 months

First QC Date

May 20, 2026

Last Update Submit

May 27, 2026

Conditions

Recurrant Inguinal Hernia

Keywords

Tapp repairRecurrant inguinal hernia

Outcome Measures

Primary Outcomes (1)

  • Feasibility and Technical Success of Laparoscopic TAPP

    Evaluation of the feasibility of the TAPP approach in recurrent inguinal hernias, measured by the rate of successful laparoscopic completion without the need for intraoperative conversion to open surgery due to severe scar tissue or adhesions.

    During the intraoperative procedure (Day of surgery)

Secondary Outcomes (7)

  • Post-operative Pain

    At 24 hours, 1 week, and 1 month post-operatively

  • Hernia Recurrence

    4 months

  • Operative Time

    During the surgical procedure (Day of surgery)

  • Length of Hospital Stay

    From the day of surgery up to hospital discharge (typically 1-2 days)

  • Incidence of Post-operative Complications

    Up to 4 months post-operatively

  • +2 more secondary outcomes

Study Arms (1)

Laparoscopic TAPP Repair

EXPERIMENTAL

Patients with recurrent inguinal hernia who will undergo laparoscopic transabdominal preperitoneal (TAPP) repair using a synthetic mesh.

Procedure: Laparoscopic Transabdominal Preperitoneal (TAPP) Repair

Interventions

Laparoscopic Transabdominal Preperitoneal (TAPP) RepairPROCEDURE

The surgical procedure will be performed under general anesthesia. Standard laparoscopic instruments will be used to access the peritoneal cavity. The peritoneum over the recurrent inguinal hernia site will be incised to enter the preperitoneal space. After reduction of the hernia sac and clearing of post-operative adhesions, a synthetic mesh will be placed to cover the hernia defects. The mesh will be secured if necessary, and the peritoneal flap will be closed using sutures or tacks.

Laparoscopic TAPP Repair

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients. Patients diagnosed with recurrent inguinal hernia. Patients fit for general anesthesia. Patients who provide informed consent.

You may not qualify if:

  • Non recurrent inguinal hernia Patients with complicated inguinal hernia. Patients unfit for general anesthesia. Patients refusing participation in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of medicine

Sohag, Egypt

RECRUITING

MeSH Terms

Interventions

tetra-4-amidinophenoxypropaneWound Healing

Intervention Hierarchy (Ancestors)

RegenerationBiological Phenomena

Central Study Contacts

marwa Saber, Resident

CONTACT

01017659722marwaelkholy93@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident of General Surgery

Study Record Dates

First Submitted

May 20, 2026

First Posted

May 27, 2026

Study Start

April 1, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

July 1, 2026

Last Updated

June 1, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)