Effect of Myofeedback and Neuromuscular Electrical Stimulation on Hemiplegic Children After Brain Tumor Resection

NCT07606222 | Completed

• 1 other identifier: Amr-phd
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

This study was conducted to compare between the effect of neuromuscular electrical stimulation and myofeedback on upper limb function, muscle activity and brain derived neurotropic factor in blood for children with hemiplegia after brain tumor surgery.

Conditions

Myofeedback; Hemiplegia; Child, Only

Outcome Measures

Primary Outcomes (1)

• Assessment of muscle activity

  All children will be assessed using surface electromyography for wrist extensor muscles while sitting, with their upper limbs resting on a desk and utilizing three electrodes. The ground electrode (black) is placed proximal to the others, the active electrode (yellow) is on the common extensor origin, and the connector (blue) is positioned at least 3 cm distally. After registering new patient data, the assessment begins via a one-channel surface electromyography setup, recording maximum and mean muscle activity during wrist extension upon pressing the play button.

  at baseline and after 12 weeks

Secondary Outcomes (3)

• Assessment of upper limb function

  at baseline and after 12 weeks

• assessment of level of neurotrophic factor

  at baseline and after 12 weeks

• assessment of dynamic spasticity of wrist and elbow flexors muscles

  at baseline and after 12 weeks

Study Arms (3)

selected physical therapy program

ACTIVE COMPARATOR

The control group will undergo a selected physical therapy (PT) program for one hour, three times weekly, over twelve weeks.

Other: selected physical therapy program

selected physical therapy program and biofeedback

EXPERIMENTAL

Patient will undergo a selected physical therapy program for one hour, three times a week, for twelve weeks, supplemented by a biofeedback program.

Other: selected physical therapy program; Device: biofeedback

selected physical therapy program and neuromuscular electric stimulation

EXPERIMENTAL

The child will participate in a physical therapy program for one hour, three times a week, over twelve weeks, supplemented by neuromuscular electric stimulation.

Other: selected physical therapy program; Device: neuromuscular electric stimulation

Interventions

selected physical therapy program OTHER

The program includes push-up exercises, active strength training for wrist extensors using fine motor toys, stretching for wrist and elbow flexors and pronators, weight-bearing positions from side sitting, quadruped position with active limb elevation, rolling a small ball with the affected limb, and rhythmic muscle approximation for shoulder, elbow, and wrist.

selected physical therapy program; selected physical therapy program and biofeedback; selected physical therapy program and neuromuscular electric stimulation

biofeedback DEVICE

During sessions, the child sits with an arm resting on a table, with electrodes placed on the wrist extensors and forearm. The treatment involves gradually increasing the intensity of faradic current to induce muscle contraction. Each session lasts 30 minutes to one hour, with treatments up to three times daily, using a frequency of 50-100 Hz and a pulse duration of 0.1-1 ms, for a duration of 2 weeks to 3 months.

selected physical therapy program and biofeedback

neuromuscular electric stimulation DEVICE

The child will participate in a physical therapy program for one hour, three times a week, over twelve weeks, supplemented by neuromuscular electric stimulation. During sessions, the child sits with an arm resting on a table, with electrodes placed on the wrist extensors and forearm. The treatment involves gradually increasing the intensity of faradic current to induce muscle contraction. Each session lasts 30 minutes to one hour, with treatments up to three times daily, using a frequency of 50-100 Hz and a pulse duration of 0.1-1 ms, for a duration of 2 weeks to 3 months.

selected physical therapy program and neuromuscular electric stimulation

Eligibility Criteria

• Age: 6 Years - 14 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Age 6-14 years post brain tumor surgery children.
• Children's hand use experience questionnaire between 25 and 50 on a scale of units.
• Grade 2 muscle power of wrist, elbow and finger extensors.
• Outpatient children.
• Post-operative brain tumour, which is located in one of the two hemispheres.
• After 6 weeks post-surgery.
• The child can follow orders and instructions.

You may not qualify if:

• Blindness.
• Deaf child.
• Skin diseases.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Elmagd physical therapy centres, Teriaq oncology centre and Elite hospital.

Alexandria, Egypt

Location

MeSH Terms

Conditions

Hemiplegia

Interventions

Biofeedback, Psychology

Condition Hierarchy (Ancestors)

Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities; Feedback, Psychological

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 17, 2026
• First Posted: May 26, 2026
• Study Start: July 1, 2024
• Primary Completion: June 1, 2025
• Study Completion: September 1, 2025
• Last Updated: May 26, 2026

Record last verified: 2026-05

Locations

EG (1)