Conditions

Termination of Pregnancy

Keywords

PGE1cervical folleystermination of pregnancy

Outcome Measures

Primary Outcomes (1)

Percentage of efficacy
It refers to the ability of PGE1 or cervical Foleys to achieve complete abortion within 48 hours during the second trimester of fetal demise
48 hours

Study Arms (2)

PGE1

EXPERIMENTAL

Group A will receive 200µg orally five doses six hours apart. If the patient did not abort after the first course, the same regimen will be repeated 24 hours after the start of the first dose of misoprostol

Drug: PGE1 tablet

cervical folleys

ACTIVE COMPARATOR

Group B will receive cervical foleys. Foley's catheter group will be put in lithotomy position in examination room, vulva vagina will be cleaned with pyodine and sterile Sim's speculum will be introduced in the vagina, holding anterior cervical lip with sponge holding forceps and with the help of another sponge holding forceps a Foleys catheter no 14 Fr will be passed in the cervix into the extra amniotic space and balloon will be inflated with 30ml saline. A urine bag will be filled with 500ml saline will be attached to the catheter for traction. As soon as the catheter will be expelled reassessment of the dilatation of the cervix will be done and if needed infusion oxytocin will be started

Device: cervical folleys

Interventions

PGE1 tabletDrug

Group A will receive 200µg orally five doses six hours apart. If the patient did not abort after the first course, the same regimen will be repeated 24 hours after the start of the first dose of misoprostol

PGE1

cervical folleysDevice

Group B will receive cervical foleys. Foley's catheter group will be put in lithotomy position in examination room, vulva vagina will be cleaned with pyodine and sterile Sim's speculum will be introduced in the vagina, holding anterior cervical lip with sponge holding forceps and with the help of another sponge holding forceps a Foleys catheter no 14 Fr will be passed in the cervix into the extra amniotic space and balloon will be inflated with 30ml saline. A urine bag will be filled with 500ml saline will be attached to the catheter for traction. As soon as the catheter will be expelled reassessment of the dilatation of the cervix will be done and if needed infusion oxytocin will be started

Eligibility Criteria

Age20 Years - 45 Years

Sexfemale(Gender-based eligibility)

Gender Eligibility DetailsFemale

Healthy VolunteersNo

Age GroupsAdult (18-64)

You may qualify if:

All women presented for termination of pregnancy (as per-operational definition).

Sponsors & Collaborators

Dr Mudassar Saeed Pansota
Otherlead

Study Sites (1)

Hilal-e-ahmar Hospital

Faisalabad, Punjab Province, 60000, Pakistan

MeSH Terms

Interventions

Alprostadil

Intervention Hierarchy (Ancestors)

Prostaglandins EProstaglandinsEicosanoidsFatty Acids, UnsaturatedFatty AcidsLipidsFatty Acids, MonounsaturatedAutacoidsInflammation MediatorsBiological Factors

Study Officials

Atiqa Noreen
Hilal-e-Ahmar Hospital, Faisalabad
PRINCIPAL INVESTIGATOR

Termination of Pregnancy in Previous Scarred Uterus: PGE1 Versus Cervical Folleys

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (2)

PGE1

cervical folleys

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (2)

PGE1

cervical folleys

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations