NCT00994734

Brief Summary

The primary aim of this study is to assess the acceptability of home-use mifepristone for termination of pregnancy among women who choose it and their providers. The investigators' secondary aims are to assess rates of follow-up, adherence, efficacy, complications, lost productivity, and to estimate the minimum proportion of women who choose home-use over clinic use of mifepristone.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
615

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2009

Geographic Reach
3 countries

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 9, 2009

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 14, 2009

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2011

Completed
Last Updated

April 17, 2012

Status Verified

April 1, 2012

Enrollment Period

1.8 years

First QC Date

October 9, 2009

Last Update Submit

April 16, 2012

Conditions

Outcome Measures

Primary Outcomes (2)

  • Proportion of women who select home-use of mifepristone

    1-2 weeks

  • Satisfaction with Method

    1-2 weeks

Study Arms (2)

clinic administration of mifepristone

NO INTERVENTION

home administration of mifepristone

EXPERIMENTAL
Drug: Mifepristone

Interventions

home administration of mifepristone

home administration of mifepristone

Eligibility Criteria

Age18 Years - 55 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Reproductive age women seeking abortion services.
  • Eligible women will be in general good health and assessed by a clinician to have an intrauterine pregnancy less than 64 days L.M.P on the day mifepristone will be taken.
  • Participants must be eligible for medical abortion according to clinician and clinic standards.
  • In the United States, women only 18 years and older will be eligible to participate, unless the study site obtains a waiver to include minors.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Feminist Women's Health Center

Atlanta, Georgia, United States

Location

Institute for Family Health

New York, New York, United States

Location

Family Health Center, Montefiore Medical Center

The Bronx, New York, United States

Location

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Location

Municipal Clinical Hospital

Chisinau, Moldova

Location

Kathmandu Medical College

Kathmandu, Nepal

Location

Nepal Medical College Teaching Hospital

Kathmandu, Nepal

Location

Related Publications (1)

  • Conkling K, Karki C, Tuladhar H, Bracken H, Winikoff B. A prospective open-label study of home use of mifepristone for medical abortion in Nepal. Int J Gynaecol Obstet. 2015 Mar;128(3):220-3. doi: 10.1016/j.ijgo.2014.09.022. Epub 2014 Nov 27.

MeSH Terms

Interventions

Mifepristone

Intervention Hierarchy (Ancestors)

EstrenesEstranesSteroidsFused-Ring CompoundsPolycyclic Compounds

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 9, 2009

First Posted

October 14, 2009

Study Start

May 1, 2009

Primary Completion

February 1, 2011

Study Completion

February 1, 2011

Last Updated

April 17, 2012

Record last verified: 2012-04

Locations