NCT07601971

Brief Summary

The main goal of this study is to compare between total Laparoscopic hysterectomy proceeded by Uterine artery cauterization at its origin and conventional total Laparoscopic hysterectomy regarding: bleeding , operative time , intra operative time and follow up post operative.

Trial Health

65
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
13mo left

Started May 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress2%
May 2026Jun 2027

First Submitted

Initial submission to the registry

July 9, 2025

Completed
10 months until next milestone

Study Start

First participant enrolled

May 15, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 22, 2026

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 15, 2027

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2027

Last Updated

May 22, 2026

Status Verified

May 1, 2026

Enrollment Period

1 year

First QC Date

July 9, 2025

Last Update Submit

May 15, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Is to compare peri operative blood loss by counting amount of blood in ml drained by suction , operation time between Conventional TLH and TLH with prior occlusion to UAs at its origin

    Is to compare peri operative blood loss by counting amount of blood in ml drained by suction , operation time between Conventional TLH and TLH with prior occlusion to UAs at its origin

    24 hours after surgery

  • Is to compare peri operative blood loss , operation time between Conventional TLH and TLH with prior occlusion to UAs at its origin

    Is to compare peri operative blood loss , operation time between conventional TLH and TLH with prior Uterine artery occlusion

    One week after surgery

Secondary Outcomes (1)

  • Post operative pain , difference in Hemoglobin level in mg /dl pre and post operative, frequency of post operative hematoma in cm detected by us at vaginal vault and ureteric complications

    24 hours postoperative

Study Arms (2)

Total Laparoscopic hysterectomy with prior uterine artery cauterization from the origin

EXPERIMENTAL

Total Laparoscopic hysterectomy with prior Uterine artery cauterization from the origin take less time and cause less bleeding

Procedure: Total Laparoscopic hysterectomy with prior Uterine artery cauterization from the origin to arm 1

Conventional Total Laparoscopic hysterectomy

EXPERIMENTAL

Conventional Total Laparoscopic hysterectomy may cause more blood loss and take more time

Procedure: Conventional Laparoscopic hysterectomy to arm 2Procedure: Total Laparoscopic hysterectomy with conventional uterine artery ligation

Interventions

Total Laparoscopic hysterectomy with prior Uterine artery cauterization from the origin to arm 1

Total Laparoscopic hysterectomy with prior uterine artery cauterization from the origin

Conventional Laparoscopic hysterectomy

Conventional Total Laparoscopic hysterectomy

Total Laparoscopic hysterectomy with ligation of uterine artery beside uterus is considered conventional and may cause more blood loss and take more time

Conventional Total Laparoscopic hysterectomy

Eligibility Criteria

Age35 Years - 55 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Good general condition of the patient ( American society of Anesthesiologists "ASA" score 1 , 2 , 3 ( Horvath et al ,. 2021) .
  • Uterine size is less than 20 weeks by fundal level . -

You may not qualify if:

  • Patients with American society of Anesthesiologists score 4 or more . ( Horvath et al ,. 2021) Uterine size is more than 20 weeks by fundal level .

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Hadeer Ali Elashry, Master degree

CONTACT

Mustafa Farag Ellakany, Lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Gynecology and obstetric resident

Study Record Dates

First Submitted

July 9, 2025

First Posted

May 22, 2026

Study Start

May 15, 2026

Primary Completion (Estimated)

May 15, 2027

Study Completion (Estimated)

June 15, 2027

Last Updated

May 22, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share