NCT07600242

Brief Summary

The goal of this clinical trial is to understand how different types of word categories, along with the language children hear from their parents, support bilingual toddlers' word learning. This study will address two main questions: (1) How are the words toddlers know related to the words their parents use? and (2) How does what toddlers already know help them learn new words in two languages? The investigators will compare bilingual toddlers with typical development to those with language delay to determine whether they learn new words in similar ways. Children's vocabulary knowledge will be assessed using standardized parent-report checklists. To examine how different types of categories support learning, the study will focus on two early-acquired categories: animals and clothing. The investigators will compare what parents report about their children's vocabulary with how children learn new words within each category. To understand the role of parent input, children and their parents will engage in shared book reading and play activities using materials from one of the target categories. Parent-child interactions will be video recorded. Children will also complete an eye-tracking task in which they learn new words in two languages within the same category.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
39mo left

Started Dec 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress12%
Dec 2025Jul 2029

Study Start

First participant enrolled

December 16, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 7, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

May 20, 2026

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2028

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2029

Last Updated

May 20, 2026

Status Verified

May 1, 2026

Enrollment Period

2.6 years

First QC Date

May 7, 2026

Last Update Submit

May 19, 2026

Conditions

Keywords

bilingualismlate talkersparent inputtoddlersword learningvocabulary

Outcome Measures

Primary Outcomes (3)

  • Word learning

    The researchers will assess learning through participants' looking behavior via experimental eye-tracking paradigms. Specifically, the researchers will measure how accurately and quickly participants look to the target object after hearing its name.

    Day 1

  • Vocabulary Network Properties

    The researchers will characterize participants' vocabulary size and structure using the MacArthur-Bates Communicative Development Inventories (MB-CDI). Vocabulary size will be calculated using the raw number of words produced (range: 0-680 words) and their age-matched percentile score from the MB-CDI (range: 0-100). Higher scores indicate larger vocabulary sizes.The researchers will also calculate how many words each participant knows in in two categories on the MB-CDI (i.e., animals \[0-43 words\] and tools \[0-28 words\]) across the languages they are learning (i.e., English and Spanish). Network properties may include the number of words in a category and the number of connections between words in a category.

    Day 1

  • Parent Language Input

    The researchers will calculate the number of words the parent says to their child during book reading and toy play activities. Language input will be defined as the total number of nouns and verbs (tokens) and the number of unique nouns and verbs (types).

    Day 1

Study Arms (2)

Toddlers with typical language development

EXPERIMENTAL

Children who have typical vocabulary sizes and do not have a history of hearing or vision impairment, neurodevelopmental disorders, or neurological or cognitive delays/disorders.

Behavioral: Large Semantic Category ConditionBehavioral: Small Semantic Category Condition

Toddlers with language delay

EXPERIMENTAL

Children whose vocabulary size is atypically small for their age in the absence of hearing impairment, neurodevelopmental disorders, or other cognitive delays.

Behavioral: Large Semantic Category ConditionBehavioral: Small Semantic Category Condition

Interventions

Participants will learn new words that refer to objects that belong to a category from which toddlers know many words (i.e., animals). They will learn new animal words in two different language conditions: a single language context and a dual language context. In the single language context, they will learn new English-like words in a learning environment where they only hear one language (i.e., English). In the dual language context, they will learn new English-like and Spanish-like words in a learning environment where they only hear both languages. Participants and their parents will also read books about animals and play with animal toy sets.

Toddlers with language delayToddlers with typical language development

Participants will learn new words that refer to objects that belong to a category from which toddlers know few words (i.e., clothing). They will learn new clothing words in two different language conditions: a single language context and a dual language context. In the single language context, they will learn new English-like words in a learning environment where they only hear one language (i.e., English). In the dual language context, they will learn new English-like and Spanish-like words in a learning environment where they only hear both languages. Participants and their parents will also read books about clothes and play with toy sets that include clothing.

Toddlers with language delayToddlers with typical language development

Eligibility Criteria

Age24 Months - 30 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • At least 10% exposure to both English and Spanish or at least 90% exposure to English and another language

You may not qualify if:

  • Hearing impairment
  • Uncorrected visual impairment
  • Neurological impairment
  • Genetic syndromes
  • Neurodevelopmental disabilities (e.g. autism)
  • More than 10% exposure to a language other than English or Spanish

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boston University

Boston, Massachusetts, 02215, United States

RECRUITING

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Model Details: A mixed-factor design where each child will be randomly assigned to one of two word learning conditions (animal or clothing). Within each condition, children will learn words in single and dual language conditions. The clinical group (toddlers with late talking) is compared to the control group (toddlers with typical development) on these conditions.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 7, 2026

First Posted

May 20, 2026

Study Start

December 16, 2025

Primary Completion (Estimated)

July 31, 2028

Study Completion (Estimated)

July 31, 2029

Last Updated

May 20, 2026

Record last verified: 2026-05

Locations