NCT07599631

Brief Summary

this study will be conducted to compare INIT versus IASTM on neck disability, cervical muscle endurance and proprioception, cervical alignment, pain intensity, pressure pain threshold in patients with neck pain

Trial Health

65
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
12mo left

Started May 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 14, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 20, 2026

Completed
5 days until next milestone

Study Start

First participant enrolled

May 25, 2026

Expected
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 25, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 25, 2027

Last Updated

May 20, 2026

Status Verified

May 1, 2026

Enrollment Period

1 year

First QC Date

May 14, 2026

Last Update Submit

May 14, 2026

Conditions

Keywords

Integrated Neuromuscular Inhibition TechniqueInstrument-Assisted Soft Tissue Mobilizationneck disabilityenduranceproprioceptionneck pain

Outcome Measures

Primary Outcomes (1)

  • neck disability

    The arabic version of Neck Disability Index (NDI) will be used. it is a 10-item, self-administered questionnaire measuring neck pain-related disability, with scores ranging from 0-50 or 0-100%. Higher scores indicate greater disability.

    up to four weeks

Secondary Outcomes (9)

  • pain intensity

    up to four weeks

  • cervical range of motion

    up to four weeks

  • joint position error (cervical proprioception)

    up to four weeks

  • pressure pain threshold

    up to four weeks

  • The Absolute Rotation Angle (ARA) C2-C7

    up to four weeks

  • +4 more secondary outcomes

Study Arms (3)

Integrated Neuromuscular Inhibition Technique

EXPERIMENTAL

twenty patients will receive the integrated neuromuscular inhibition technique plus traditional therapy three times a week for four weeks

Other: Integrated Neuromuscular Inhibition TechniqueOther: tradional therapy

Instrument-Assisted Soft Tissue Mobilization

EXPERIMENTAL

twenty patients will receive instrument-assisted soft tissue mobilization plus traditional therapy three times a week for four weeks

Other: Instrument-Assisted Soft Tissue MobilizationOther: tradional therapy

traditional therapy

ACTIVE COMPARATOR

twenty patients will receive traditional therapy three times a week for four weeks

Other: tradional therapy

Interventions

For the integrated neuromuscular inhibition technique, the participant will be in a supine lying position. During the PPT evaluation process, the site of the TrP will be determined and will be marked. First, intermittent IC will be initiated by using the thumb and index finger to apply a pincer grip to the TrP in the middle of the UT. Second, applying pressure to the trigger point and asking the participants how much pain they will experience. The participants' heads will passively flexed laterally to the affected side. The therapist then will hold the participant's forearm and passively will move the shoulder to about 90° of abduction while monitoring the discomfort induced by the TrP, and then will ask the patient about the intensity of pain. If the pain will decrease by 70% from the start, the position will be held for 30 seconds and repeated 2 to 3 times. Then muscle energy technique is applied plus tradional therapy.

Integrated Neuromuscular Inhibition Technique

For IASTM, the M2T blade will be used to identify specific parts of the limitation on the right UT. After that, treatment planes 1-2-3 will be used. Prior to treatment, Vaseline will be applied as a lubricant to the skin around the neck area, and an alcohol pad will be used to clean the instrument. Then, using an M2T blade at a 45° angle, long, slow strokes over the muscle will be performed, beginning at its insertion and ending at its origin, for 2 to 3 minutes . If the participant felt a burning sensation, it will be instructed to apply an ice pack plus tradional therapy.

Instrument-Assisted Soft Tissue Mobilization

the patients will receive tradional therapy in the form of 10 minutes of moist heat (hot pack) isometric strengthening exercises for all cervical muscles by applying manual resistance on the side of the head for side bending, the occiput for extension, and the forehead for flexion.The resistance will be sustained for 10 seconds and repeated 10 to 15 times, then they will receive stretching exercises for extensor muscles for 30 seconds and repeated 3 times in every session. Finally, active ROM exercises for the neck and chin will be performed

Instrument-Assisted Soft Tissue MobilizationIntegrated Neuromuscular Inhibition Techniquetraditional therapy

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • All participants ages will range from 18 to 50 years.
  • BMI ranged from 18.5 to 30.
  • have TrPs in their UT muscle, pain at rest, a jump sign when pressure is applied, limited range of motion (ROM), and referred pain.
  • The participants will report pain in the posterior or posterior lateral aspect of the neck in the previous 3 months

You may not qualify if:

  • Participants of cervical spine disorders (cervical disc disease, cervical spondylitis, cervical myelopathy.
  • Participants with musculoskeletal conditions.
  • Pregnant women.
  • Participants with congenital postural deformities.
  • Participants who had a definite visual disability.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Neck Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Nabil Abdel-Aal, professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
opaque sealed envelope
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: integrated Neuromuscular Inhibition Technique and Instrument-Assisted Soft Tissue Mobilization
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator : nabil mahmoud ismail

Study Record Dates

First Submitted

May 14, 2026

First Posted

May 20, 2026

Study Start (Estimated)

May 25, 2026

Primary Completion (Estimated)

May 25, 2027

Study Completion (Estimated)

May 25, 2027

Last Updated

May 20, 2026

Record last verified: 2026-05