NCT07599020

Brief Summary

To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for not_applicable

Timeline
7mo left

Started Jul 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 17, 2026

Completed
4 months until next milestone

First Posted

Study publicly available on registry

May 20, 2026

Completed
2 months until next milestone

Study Start

First participant enrolled

July 10, 2026

Expected
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 12, 2026

2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 10, 2027

Last Updated

May 20, 2026

Status Verified

May 1, 2026

Enrollment Period

5 months

First QC Date

January 17, 2026

Last Update Submit

May 16, 2026

Conditions

KeratoconusIntraocular Pressure

Outcome Measures

Primary Outcomes (1)

  • Intraocular pressure will be measured by using Corvis CT before cross linking and one month after cross linking

    Recording the intraocular pressure

    Through the end of the study in approximately one year

Study Arms (1)

Measuring the intraocular pressure after cross linking

OTHER

Measuring the intraocular pressure by using different techniques after corneal cross linking

Device: Corvis Machine

Interventions

Corvis MachineDEVICE

Measuring the intraocular pressure

Measuring the intraocular pressure after cross linking

Eligibility Criteria

Age19 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patients who will corneal cross linking for mild degree of keratoconus, age between 19 and 35 years old

You may not qualify if:

  • Corneal scarring.
  • Previous corneal infections.
  • Minimum corneal thickness at the thinnest location less than 400 µm.
  • History of uveitis or ocular allergy.
  • Pre-existing glaucoma.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Keratoconus

Condition Hierarchy (Ancestors)

Corneal DiseasesEye Diseases

Central Study Contacts

Tamer Ibrahim, Ass professor of ophthalmology

CONTACT

+201001243049dinasabry71@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor of ophthalmology

Study Record Dates

First Submitted

January 17, 2026

First Posted

May 20, 2026

Study Start (Estimated)

July 10, 2026

Primary Completion (Estimated)

December 12, 2026

Study Completion (Estimated)

February 10, 2027

Last Updated

May 20, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will share

The statistical analysis results will be shared through the manuscript