PENG vs. Femoral Nerve Block for Pain Control in Hip Surgery

NCT07597551 | Not Yet Recruiting

• 1 other identifier: MD.18.7.2025
• Study Type: interventional
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to compare the efficacy of the ultrasound- guided pericapsular nerve group (PENG) block versus the femoral nerve block (FNB) for postoperative pain control in patients undergoing hip surgeries, specifically evaluating pain scores and quadriceps strength.

Conditions

Pain, Postoperative

Outcome Measures

Primary Outcomes (1)

• Visual Analog Scale (VAS) Score for Pain at 24 Hours.

  A scale from 0 to 10 (0 = no pain, 10 = worst imaginable pain). Patients will be asked to rate their pain level at rest.

  24 hours postoperatively.

Secondary Outcomes (2)

• Quadriceps Muscle Strength

  6, 12, and 24 hours post-op.

• Total Opioid Consumptiont

  First 3 days

Study Arms (2)

PENG block group

EXPERIMENTAL

Participants in this group will receive a preoperative, ultrasound-guided Pericapsular Nerve Group (PENG) block. Under sterile conditions and ultrasound guidance (curvilinear or linear probe), the needle will be inserted in-plane to target the facial plane between the psoas tendon and the pubic ramus. A volume of 20-25 mL of 0.25% Bupivacaine will be injected following negative aspiration

Procedure: PENG BLOCK

Femoral nerve block group

ACTIVE COMPARATOR

Participants in this group will receive a preoperative, ultrasound-guided Femoral Nerve Block (FNB). Using a linear probe, the femoral nerve will be identified lateral to the femoral artery and deep to the fascia iliaca. A volume of 20-25 mL of 0.25% Bupivacaine will be injected to achieve circumferential spread around the nerve trunk

Procedure: Femoral nerve block

Interventions

PENG BLOCK PROCEDURE

Regional anesthesia technique involving the injection of local anesthetic into the myofascial plane between the psoas muscle and the iliopubic eminence.

Also known as: Pericapsular Nerve Group block

PENG block group

Femoral nerve block PROCEDURE

Regional anesthesia technique involving the injection of local anesthetic deep to facia iliaca and lateral to femoral artery circulating femoral nerve trunk.

Also known as: FNB

Femoral nerve block group

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 40 years or older.
• Presenting for hip surgeries
• No contraindications to regional anesthesia.
• Time of surgery up to 3 hours
• ASA I-III
• Able to provide written informed consent.
• Able to reliably report pain and other symptoms to the research team.
• Undergoing elective or emergency hip surgeries.

You may not qualify if:

• Inability to provide first-person consent due to cognitive impairment.
• Presence of a language barrier that would preclude reliable reporting of symptoms or understanding study procedures.
• More than ASA III. 4
• Previous neurological deficit in the lower limbs.
• Local infection at block area.
• Lengthy surgeries more than 3 hours.

Sponsors & Collaborators

• Benha University: lead

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• Taghreed Saker, MD

  Benha University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed I Swera, Master

CONTACT

00201005818338; mohamedswera86@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asistant lecetruer

Model Details: Participants are randomized into two distinct groups. Group A: Receives the PENG block. Group B: Receives the Femoral Nerve Block (FNB). Flow: Each patient stays in their assigned group for the duration of the study

Study Record Dates

• First Submitted: January 24, 2026
• First Posted: May 19, 2026
• Study Start: May 15, 2026
• Primary Completion (Estimated): May 15, 2027
• Study Completion (Estimated): May 15, 2027
• Last Updated: May 19, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share