Post-osteoporotic Fracture Exercise Program

NCT07595991 | Not Yet Recruiting

• 1 other identifier: 127410
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Those with osteoporosis often have weaker bones and this leads to higher chances of fractures. Therefore, the investigators want to evaluate the feasibility and safety of group exercise classes specifically designed for individuals with osteoporosis who had an osteoporotic fracture. By focusing on this high-risk population, the investigators want to see whether such exercise interventions can be an option for improving bone health, reducing the risk of future fractures, and enhancing physical function without compromising safety.

Conditions

Osteoporosis; Osteoporotic Fracture

Keywords

Osteoporosis; Exercise Intervention; Osteoporotic fracture

Outcome Measures

Primary Outcomes (3)

• Recruitment Feasibility

  Recruitment feasibility will be assessed by the number of participants enrolled in the study over a 12-month recruitment period. The target recruitment goal is 100 participants.

  Assessed over 12 months

• Retention Feasibility

  Retention feasibility will be assessed as the percentage of enrolled participants who complete the 12-week reassessment. The predefined retention target is 60%. Percentages range from 0% to 100%, with higher percentages indicating better retention feasibility.

  Assessed at 12 weeks

• Exercise Class Adherence

  Exercise adherence will be assessed using class attendance records. Adherence will be calculated as the percentage of scheduled exercise sessions attended by each participant. The predefined adherence target is 80%. Percentages range from 0% to 100%, with higher percentages indicating better adherence.

  Assessed over the 12-week intervention period

Secondary Outcomes (2)

• Program Acceptability

  Assessed at 12 weeks

• Intervention Safety

  Assessed throughout the 12-week intervention period

Other Outcomes (10)

• Change in Bone Quality

  Baseline and 12 weeks

• Change in health care utilization

  Assessed over the 6-month period following completion of the exercise program

• Change in Physical Function

  Baseline, 6 weeks, and 12 weeks

Study Arms (1)

Experimental Arm for Feasibility study

EXPERIMENTAL

Feasibility Intervention

Other: Exercise Program

Interventions

Exercise Program OTHER

Participants complete a 12-week, twice weekly, whole body group exercise program. Participants will also complete qualitative interviews and DXA bone scans.

Experimental Arm for Feasibility study

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed with osteoporosis.
• History of low trauma fracture within the past year
• Cleared for physical activity using the get active questionnaire, 100 bpm resting heart rate or less, 160 mm Hg diastolic blood pressure or less
• Able to understand and provide informed consent.
• Residing within the study's geographic area (e.g., London, Ontario).

You may not qualify if:

• Individuals who do not understand the English language
• Medical conditions contraindicating participation in exercise (e.g., uncontrolled cardiovascular disease, severe respiratory illness).
• Cognitive impairments that prevent informed consent or participation.
• Recent major surgeries or medical events limiting physical activity.
• Participation in conflicting clinical trials or rehabilitation programs.
• Residents outside the designated study area.

Sponsors & Collaborators

• Western University, Canada: lead

Study Sites (1)

Canadian Centre for Activity and Aging

London, Ontario, N6G 1H1, Canada

Location

MeSH Terms

Conditions

Osteoporosis; Osteoporotic Fractures

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Fractures, Bone; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Christina Ziebart, PT, PhD

CONTACT

519-661-2111; cziebart@uwo.ca

Abigail Mitchell, BSc

CONTACT

709-727-2762; amitc57@uwo.ca

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 28, 2026
• First Posted: May 19, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): February 1, 2028
• Last Updated: May 19, 2026

Record last verified: 2026-05

Locations

CA (1)