Evaluation of a Virtual Reality-based Version of the Multiple Errands Test in Alcohol Use Disorder
EVIMETAL
1 other identifier
interventional
90
1 country
2
Brief Summary
The goal of this study is to validate the virtual version of the Multiple Errands Test (V-MET) as a tool for assessing executive functions in patients with alcohol use disorder (AUD). More specifically, the project aims to:
- 1.evaluate if the performance in the virtual version of the test is related to the performance in the original test in patients with AUD.
- 2.establish whether the virtual version of the test is sensitive enough to detect patients with or without an executive function deficit.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2026
Typical duration for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2026
CompletedFirst Submitted
Initial submission to the registry
May 12, 2026
CompletedFirst Posted
Study publicly available on registry
May 18, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2028
May 20, 2026
May 1, 2026
2.1 years
May 12, 2026
May 18, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Total number of errors on the test
Total number of errors on the MET and the V-MET. Errors include: * Inefficiencies (a more effective action could have been made) * Rule breaks: a specific rule is broken * Interpretation failure (the task is misunderstood or misinterpreted) * Task failure: not carried out or not completely completed
Baseline
Secondary Outcomes (4)
Inefficiencies on the test
Baseline
Rule breaks on the test
Baseline
Interpretation failures on the test
Baseline
Task failures on the test
Baseline
Study Arms (3)
AUD group with executive function deficit
EXPERIMENTALGroup of patients with alcohol use disorder and a deficit in executive functions as assessed by the Frontal Assessment Battery
AUD group without executive function deficit
ACTIVE COMPARATORGroup of patients with alcohol use disorder but without a deficit in executive functions as assessed by the Frontal Assessment Battery
Control group
ACTIVE COMPARATORGroup of healthy volunteers
Interventions
The test takes place in a real supermarket. Participants must complete a list of tasks (e.g., purchasing certain items, collecting some information) while adhering to rules (e.g., not visiting the same place twice, etc).
The test takes place in a virtual supermarket, developed on the C2Neuro app by C2CARE®. Participants must complete a similar list of tasks to the MET (e.g., purchasing certain items, collecting some information) and adhere to similar to rules (e.g., not visiting the same place twice, etc) .
Eligibility Criteria
You may qualify if:
- written consent
- Normal or corrected vision and hearing
- Membership or entitlement to a social security plan
- spoken and written French
- third party liability insurance
- for patients only :
- at least 6 criteria for AUD based on the Diagnostic and statistical manual of mental disorders
- At the end of withdrawal: treatment with a diazepam equivalent of ≤ 20 mg/day
You may not qualify if:
- under tutorship/ judicial protection
- Sensory or motor impairment (impeding the use of virtual reality and/or mobility)
- Severe neurological disorder (such as dementia or Korsakoff's syndrome)
- Photosensitive epilepsy (contraindication for the use of virtual reality)
- Any other condition deemed incompatible with the study, at the investigator's discretion
- Montreal Cognitive Assessment (MoCA) score \< 10 (severe cognitive impairment)
- Breastfeeding or pregnant women
- Familiarity with the supermarket visited during the MET test
- For controls only :
- History of alcohol use disorder
- score ≥ 8 on the Alcohol Use Disorders Identification Test
- Score on the Frontal Assessment Battery \< 16 (or \< 15 if education is below secondary level)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
CH Le Vinatier
Bron, 69500, France
Hôpital de la Croix Rousse
Lyon, 69004, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Christophe ICARD, MD
CH Le Vinatier
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 12, 2026
First Posted
May 18, 2026
Study Start
May 1, 2026
Primary Completion (Estimated)
June 1, 2028
Study Completion (Estimated)
June 1, 2028
Last Updated
May 20, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- ANALYTIC CODE
- Time Frame
- Data and supporting documents will be available beginning at the time of publication of the primary results
- Access Criteria
- Data will be made openly available
Individual participant data (IPD) underlying the results reported in this study might be shared, including de-identified demographic data, baseline characteristics, outcome measures, and variables necessary to reproduce the analyses. All data will be fully anonymized to protect participant confidentiality. A data dictionary and relevant metadata might also be provided to facilitate interpretation and reuse. The analytic code will be provided at the time of publication of the primary study results. De-identified IPD will be shared via an open science repository such as Open Science Framework and may also be made available upon request.