Acceptability and Feasibility Study of Non-alcoholic Beverages

NCT07451574 | Enrolling By Invitation

• 2 other identifiers: 839971K99AA031716
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This project will elucidate the acceptability and feasibility of incorporating provision of non-alcoholic beers into alcohol use disorder treatment, for patients interested in using non-alcoholic beers as part of their recovery from alcohol use disorder.

Conditions

Alcohol Use Disorder (AUD)

Keywords

non-alcoholic beer; alcohol

Outcome Measures

Primary Outcomes (8)

• Participant Beverage Satisfaction (Acceptability)

  "How satisfied were you with the beverages you received in this study?" with 5-pt scale response options ranging from "Very Unsatisfied" to "Very Satisfied." Higher scores \[split by condition\] will indicate greater acceptability.

  Assessed at the end of week 6

• Participant Intention to Consume Assigned Beverage in the Future (Acceptability)

  "Do you intend to consume the beverage type you received in the future?" with 5-pt scale response options ranging from "Definitely not" to "Definitely." Higher scores \[split by condition\] will indicate greater acceptability.

  Assessed at the end of week 6

• Participant Likelihood of Recommending Beverage (Acceptability)

  "Would you recommend the use of the beverage type you received for people who have alcohol use disorder?" with 5-pt scale response options ranging from "Definitely not" to "Definitely." Higher scores \[split by condition\] will indicate greater acceptability.

  Assessed at the end of week 6

• Screened Out of Contacted (Feasibility)

  Percentage of participants who completed the screening measure out of those who were contacted. Higher percentage will indicate greater feasibility.

  Beginning of recruitment to end of recruitment (approximately 3-6 months)

• Eligible Out of Screened (Feasibility)

  Percentage of participants who screen eligible out of those who were screened. Higher percentage will indicate greater feasibility.

  Beginning of recruitment to end of recruitment (approximately 3-6 months)

• Enrolled Out of Eligible (Feasibility)

  Percentage of participants who enrolled out of those who screened eligible. Higher percentage will indicate greater feasibility.

  Beginning of recruitment to end of recruitment (approximately 3-6 months)

• Retention (Feasibility)

  Percentage of participants who completed the study out of those who enrolled. Higher percentage \[split by condition\] will indicate greater feasibility.

  Beginning of recruitment to end of data collection (approximately 3-6 months)

• Perception of Beverage Supply (Feasibility)

  Percentage of participants whose response to "How was the supply of beverages you received throughout the study?" is "just right" \[as opposed to "too little" or "too much"\]. Higher percentage \[split by condition\] will indicate greater feasibility.

  Assessed at the end of week 6

Secondary Outcomes (8)

• Average Blood Alcohol Content Across 6 Weeks

  Study weeks 1-6

• Change in Blood Alcohol Content Across 6 Weeks

  Treatment entry to week 6

• Average Number of Days with Breathalyzer Readings

  Assessed at 6 weeks.

• Median Number of Breathalyzer Readings Among Days with Readings

  Assessed at 6 weeks.

• Change in Reported Alcohol Use

  Baseline to 6 weeks.

Study Arms (2)

Non-alcoholic beer

EXPERIMENTAL

Participants will receive non-alcoholic beers (volume matching alcohol volume intake prior to alcohol use disorder treatment enrollment) for 6 weeks.

Other: Non-alcoholic beer

Sparkling water

OTHER

Participants will receive sparkling water (volume matching alcohol volume intake prior to alcohol use disorder treatment enrollment) for 6 weeks.

Other: Sparkling water

Interventions

Non-alcoholic beer OTHER

Participants will receive non-alcoholic beers and will be encouraged to consume the beverages to the extent they find useful/desirable during the 6-week study period.

Non-alcoholic beer

Sparkling water OTHER

Participants will receive sparkling water and will be encouraged to consume the beverages to the extent they find useful/desirable during the 6-week study period.

Sparkling water

Eligibility Criteria

• Age: 21 Years - 89 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants will be eligible if they report on the screening survey:
• living in California and provide a California mailing address (to ship study materials to)
• consuming ≤42 alcoholic beverages per week (as we seek to provide an equal count of the substitute beverage and budgetary restrictions prevent an amount greater than that)
• having alcohol use disorder documented with ≥2 symptoms on the Alcohol Symptom Checklist
• being enrolled in Ria Health treatment
• having English language fluency

Sponsors & Collaborators

• Stanford University: lead
• National Institute on Alcohol Abuse and Alcoholism (NIAAA): collaborator

Study Sites (1)

Stanford Prevention Research Center

Stanford, California, 94304, United States

Location

MeSH Terms

Conditions

Alcoholism

Interventions

Carbonated Water

Condition Hierarchy (Ancestors)

Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Mineral Waters; Water; Hydroxides; Alkalies; Inorganic Chemicals; Anions; Ions; Electrolytes; Oxides; Oxygen Compounds; Carbonated Beverages; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Drinking Water; Food and Beverages

Study Officials

• Molly A Bowdring, PhD

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Instructor

Study Record Dates

• First Submitted: February 27, 2026
• First Posted: March 5, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): August 1, 2026
• Last Updated: April 30, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: ANALYTIC CODE
• Time Frame: Analytic code, data, and data dictionary will be uploaded upon at the time of primary results submission to an academic journal.

Locations

US (1)