NCT07592793

Brief Summary

The goal of this study is to evaluate the impact of a multi-level intervention on cancer prevention and social determinants of health outcomes. This partnership between academic and community-based researchers aims to link community health centers and communities in ways that maximize both civic engagement and participation in cancer control care. The system-level intervention consists of two components: (1) provision of community health center systems-level tools for cancer screening (breast, cervical, colorectal) and tobacco cessation treatment gaps; and (2) digital access screening and navigation. These interventions will be delivered via usual care.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
38mo left

Started Jun 2026

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 4, 2026

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 18, 2026

Completed
14 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Expected
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2028

1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2029

Last Updated

May 18, 2026

Status Verified

May 1, 2026

Enrollment Period

2 years

First QC Date

May 4, 2026

Last Update Submit

May 11, 2026

Conditions

Outcome Measures

Primary Outcomes (4)

  • Patients Screened for Colorectal Cancer

    % patients who are up to date on colorectal cancer screening from EMR

    change from baseline to end of intervention period, an average of 1 year

  • Patients Screened for Breast Cancer

    % patients who are up to date on breast cancer screening from EMR

    change from baseline to end of intervention period, an average of 1 year

  • Patients Screened for Cervical Cancer

    % patients who are up to date on cervical cancer screening from EMR

    change from baseline to end of intervention period, an average of 1 year

  • Patients Offered Pharmacotherapy for Smoking Cessation

    % patients offered pharmacotherapy from EMR

    change from baseline to end of intervention period, an average of 1 year

Secondary Outcomes (2)

  • Acceptability of the intervention

    Post intervention, 1 year follow up

  • Feasibility of the intervention

    Post intervention, 1 year follow up

Study Arms (2)

Multilevel Intervention

EXPERIMENTAL
Behavioral: Tools and Training for Cancer ControlBehavioral: Enhancing Social Capital and Civic Engagement

Usual Care

NO INTERVENTION

In this stepped wedge design, all sites have a period of being in usual care. Six sites then have periods of providing the intervention and six sites remain comparison sites (i.e. usual care).

Interventions

This system level intervention consists of two components: (1) provision of community health center systems-level tools for cancer screening (breast, cervical, colorectal) and tobacco cessation treatment gaps; and (2) digital access screening and navigation.

Multilevel Intervention

This community level intervention consists of a patient referral from a community health center to a community organization focused on building social capital and civic engagement to test the impact of connecting clinical and community resources explicitly for patients.

Multilevel Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Community health center staff or community partners
  • Age 18 or older

You may not qualify if:

  • Under 18
  • Patients will not be individually recruited for the study because the intervention is being offered as part of routine care.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Tobacco Use Cessation

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
SEQUENTIAL
Model Details: This study uses a cluster-randomized, stepped-wedge design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer on Social and Behavioral Sciences

Study Record Dates

First Submitted

May 4, 2026

First Posted

May 18, 2026

Study Start (Estimated)

June 1, 2026

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

July 1, 2029

Last Updated

May 18, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will share

Data that underlie the results reported here, after de-identification. Individual staff/partner data on implementation will be made publicly available. Patient data can be made available upon request and appropriate approvals (see below).

Time Frame
Data will be stored for 7 years.
Access Criteria
Outside investigators will need an approved concept proposal to analyze study data and spend the requisite time with study staff to learn about the data elements needed to conduct the proposed analysis. With the assistance from the study's analytic team, s/he will draft a detailed analysis plan and present to the core group of co-investigators. The discussion at this meeting ensures adequate knowledge of the data, and the presenter gains much insight into how the analysis can be most useful and how it relates to previous analyses. Once the plan is approved by this group, it must also be approved by the CHCs that provide the de-identified data. Following approval by the appropriate IRBs and confirmation that it meets HIPAA requirements, s/he may sign a DUA to use a secure, de-identified dataset to complete only the approved analyses and write the manuscript(s) offsite. A formal data analysis plan application and DUA are available. Requests should be directed to jdaly@hsph.harvard.edu.