Detection of Scoliosis

NCT07581015 | Not Yet Recruiting DMC

• 1 other identifier: IRAS: 357368
• Study Type: observational
• Target: 500
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to evaluate whether plantar pressure data collected during standing and walking can be used with machine learning to support early detection of scoliosis in young people. Patients with scoliosis and healthy volunteers aged 10-18 will undergo a short assessment using a pressure mat.

Conditions

Adolescent Idiopathic Scoliosis (AIS)

Outcome Measures

Primary Outcomes (1)

• A classification model based on ML using plantar pressure data to distinguish between scoliosis patients and healthy volunteers.

  6 months after data collection

Study Arms (2)

scoliosis patients

healthy volunteers

Eligibility Criteria

• Age: 10 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Young people aged 10-18 years will be recruited from scoliosis clinics at the Royal National Orthopaedic Hospital (patients with a confirmed diagnosis of scoliosis) and through community recruitment for healthy volunteers. Eligible participants must be able to stand and/or walk on a pressure mat.

You may qualify if:

• Healthy Controls: Adolescents without any spinal condition or significant musculoskeletal issues, and with no prior history of scoliosis, to provide normal plantar pressure data for comparison.
• Scoliosis Diagnosis: Adolescents diagnosed with adolescent idiopathic scoliosis (AIS) by a healthcare professional (through clinical evaluation and/or radiographic assessment) are eligible.
• Age: Participants must be between the ages of 10 and 18 years at the time of recruitment.
• Willingness to Participate: Participants and their parent(s)/guardian(s) must provide informed consent/assent prior to participation.
• Ability to Complete Study Procedures: Participants must be able to complete the plantar pressure measurement test, which requires standing on a pressure mat for a few minutes.

You may not qualify if:

• Severe Pain or Discomfort: Participants unable to stand or walk comfortably due to pain or musculoskeletal issues.
• Non-cooperation: Participants who are unable or unwilling to follow instructions or consent/assent procedures.
• Uncontrolled Medical Conditions: Adolescents with uncontrolled conditions (e.g., cardiovascular or endocrine disorders) compromising participation.
• Recent Foot Injuries or Conditions: Participants with foot injuries or conditions (e.g., wounds, infections) that may interfere with plantar pressure measurement.

Sponsors & Collaborators

• University College, London: lead
• Xinhua Hospital, Shanghai Jiao Tong University School of Medicine: collaborator
• Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University: collaborator

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 5, 2026
• First Posted: May 12, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): July 1, 2027
• Study Completion (Estimated): July 1, 2028
• Last Updated: May 12, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: ANALYTIC CODE