NCT07577492

Brief Summary

This study aims to investigate the relationship between cervical position sense, core stabilization, and postural balance in university students aged 18-30 years with Upper Crossed Syndrome (UCS). Upper Crossed Syndrome is a common musculoskeletal disorder characterized by muscle imbalance, including weakness of the deep cervical flexors, middle and lower trapezius, rhomboids, and serratus anterior, along with tightness of the upper trapezius, levator scapulae, sternocleidomastoid, and pectoralis major and minor. This condition frequently affects university students due to prolonged sitting, extensive computer use, and poor posture. While previous research has focused on discrete components of UCS such as posture correction or pain management, the combined effects of cervical proprioception, core stability, and postural balance remain poorly understood. A total of 48 participants will be enrolled and divided into two equal groups: 24 students diagnosed with Upper Crossed Syndrome and 24 healthy students as a control group. Assessments include cervical joint position error testing, core stabilization endurance tests (Unilateral Hip Bridge Endurance Test and Sahrmann Five-Level Core Stability Test), static balance evaluation using the Balance Error Scoring System (BESS), and dynamic balance assessment using the Y-Balance Test. Pain intensity will be measured using the Visual Analog Scale (VAS). This study will help identify neuromuscular and sensory mechanisms underlying these parameters and support evidence-based rehabilitation techniques to improve postural alignment, reduce musculoskeletal dysfunction, and enhance overall functional performance in this population.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for all trials

Timeline
0mo left

Started Apr 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress83%
Apr 2026May 2026

Study Start

First participant enrolled

April 20, 2026

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

May 4, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 11, 2026

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 25, 2026

Expected
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Last Updated

May 19, 2026

Status Verified

April 1, 2026

Enrollment Period

1 month

First QC Date

May 4, 2026

Last Update Submit

May 15, 2026

Conditions

Keywords

neck paincervical position senseupper crossed syndromecore stabilizationpostural controlproprioception

Outcome Measures

Primary Outcomes (3)

  • Cervical Joint Position Error (JPE)

    Measurement of cervical proprioceptive acuity using the Joint Position Error test. Participants actively move their head into extension, left rotation, and right rotation, then attempt to return to the neutral position with eyes closed. The repositioning error is measured in centimeters using a laser pointer mounted on a headband and a target grid positioned at eye level on the wall. Three trials are performed in each movement direction, and the mean repositioning error is calculated. Larger errors indicate impaired cervical position sense.

    Baseline (single assessment session, approximately 5 minutes during the visit)

  • Core Stabilization Endurance

    Evaluation of core muscle endurance and lumbopelvic stability using two tests: (1) Unilateral Hip Bridge Endurance (UHBE) Test: participant lies supine with knees bent, extends one leg, and raises hips into a bridge position. Time maintained without hip sag or body misalignment is recorded in seconds for both sides. (2) Sahrmann Five-Level Core Stability Test: participant in supine with Pressure Biofeedback Unit (PBU) placed under lumbar spine (inflated to 40 mmHg). Participant performs progressively challenging leg movements across five levels while maintaining pressure at 40 mmHg (±10 mmHg). The highest successfully completed level is recorded.

    Baseline (single assessment session, approximately 10 minutes during the visit)

  • Postural Balance Performance

    Evaluation of static and dynamic balance using two tests: (1) Balance Error Scoring System (BESS) for static balance: participant maintains stability in six stances (double-leg, single-leg, and tandem) on firm and foam surfaces while eyes closed. Number of postural deviations or "errors" is counted; higher scores indicate poorer balance. (2) Y-Balance Test for dynamic balance: participant stands on one limb while reaching with contralateral limb in anterior, posteromedial, and posterolateral directions. Reach distances are measured in centimeters, normalized to limb length, and averaged across three trials for each direction.

    Baseline (single assessment session, approximately 15 minutes during the visit)

Study Arms (2)

upper crossed syndrome group

Participants diagnosed with Upper Crossed Syndrome (UCS) based on postural assessment, including forward head posture (CVA \< 49°), rounded shoulder posture (\> 2.5 cm), and presence of chronic neck pain. No intervention was administered. Participants underwent assessments of cervical position sense (Joint Position Error test), core stabilization (Unilateral Hip Bridge Endurance test and Sahrmann Five-Level Core Stability test), static balance (Balance Error Scoring System), and dynamic balance (Y-Balance Test). Pain intensity was measured using the Visual Analog Scale (VAS).

Other: postural and balance assessment battery

healthy control group

Healthy university students aged 18-30 years without any diagnosis of Upper Crossed Syndrome, forward head posture, rounded shoulders, or chronic neck pain. No intervention was administered. Participants underwent the same assessments as the UCS group: cervical position sense (Joint Position Error test), core stabilization (Unilateral Hip Bridge Endurance test and Sahrmann Five-Level Core Stability test), static balance (Balance Error Scoring System), dynamic balance (Y-Balance Test), and pain assessment using the Visual Analog Scale (VAS).

Other: postural and balance assessment battery

Interventions

A comprehensive assessment battery including cervical joint position error testing, core stabilization endurance tests (Unilateral Hip Bridge Endurance Test and Sahrmann Five-Level Core Stability Test), static balance evaluation using the Balance Error Scoring System (BESS), dynamic balance assessment using the Y-Balance Test, and pain intensity measurement using the Visual Analog Scale (VAS). Total assessment time approximately 25-35 minutes.

healthy control groupupper crossed syndrome group

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

The study population consists of university students aged 18-30 years from Istinye University and other universities in Istanbul. Participants will be recruited from various academic disciplines. The target population includes students with Upper Crossed Syndrome (UCS) for the case group and healthy students without UCS for the control group. Recruitment will be conducted through flyers posted across campus buildings, advertisements on student social media platforms, mass emails to all university departments, direct screening in common areas, and an online screening survey for volunteers.

You may qualify if:

  • University students aged 18-30 years.
  • Diagnosis of Upper Crossed Syndrome (UCS) confirmed by postural assessment.
  • Forward Head Posture with Craniovertebral Angle (CVA) less than 49 degrees.
  • Rounded Shoulder Posture greater than 2.5 cm.
  • Presence of chronic neck pain.
  • Impaired cervical position sense.

You may not qualify if:

  • History of cervical spine surgery.
  • Neurological disorders (e.g., stroke, multiple sclerosis, Parkinson's disease).
  • Acute musculoskeletal injury to the neck, back, or upper extremities within the past 3 months.
  • Previous traumatic injuries to the neck or back.
  • Any diagnosed vestibular or balance disorder.
  • Visual impairment that affects balance.
  • Pregnancy.
  • Participation in another interventional clinical trial within the past 30 days.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istinye Uni

Istanbul, Topkapi, 34010, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type PreusNeck Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Nalan Soydaş Engin, Phd

    Istinye University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

abdelrahman borham, Msc

CONTACT

nalan Soydaş Engin, Ass prof

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physical Therapy Specialist and Master's Student.

Study Record Dates

First Submitted

May 4, 2026

First Posted

May 11, 2026

Study Start

April 20, 2026

Primary Completion (Estimated)

May 25, 2026

Study Completion (Estimated)

May 30, 2026

Last Updated

May 19, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations