Influence of Keratinized Tissue Width and Attached Gingiva Width on Root Coverage in Patients With Recession Defects: A Prospective Clinical Study

NCT07576439 | Not Yet Recruiting DMC

• 1 other identifier: Dr. Richa Tirkey Periodontics
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the association between the width of keratinized tissue and attached gingiva with root coverage outcomes in RT1 gingival recession defects of maxillary and mandibular anterior teeth treated with subepithelial connective tissue graft using a minimally invasive technique (VISTA + CTG).

1. 1.PRIMARY OBJECTIVES A. To analyze relation and association at 3 and 6 months outcomes in terms of CRC, mean RC and gingival margin position with baseline parameters including width of keratinized tissue and width of attached gingiva, after providing mucogingival plastic surgery in the form of VISTA+CTG for the treatment of RT1recession defects.
2. 2.SECONDARY OBJECTIVES A. To access recession depth (RD), recession width (RW), probing pocket depth (PPD), mid buccal clinical attachment loss (b CAL), change in gingival thickness (GT) at baseline, at 3 months and 6 months.
3. 3.Study design and setting The present clinical trial will be conducted in the department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana.
4. 4.Study period- up to 24 months
5. 5.Study subjects INCLUSION CRITERIA
6. 6.Patients with Millers class Ⅰ and II / RT1 isolated recession defects in labial maxillary and mandibular anterior teeth region.
7. 7.Recession depth ≥2mm
8. 8.Systemically healthy individuals.
9. 9.Age \>18 years old.
10. 10.Full mouth bleeding and plaque score ≤20%
11. 11.Patients who agreed to participate in the study and signed an informed consent form.
12. 12.Patients having systemic disease such as hypertension, diabetes, hyperthyroidism or on medication that influence the outcome of periodontal therapy.
13. 13.Patient with active periodontal disease
14. 14.Smokers and tobacco users
15. 15.Mal-aligned anterior teeth.
16. 16.Patients who had already undergone root coverage procedure on the selected site.
17. 17.Pregnant and lactating females
18. 18.Involved tooth with trauma from occlusion.
19. 19.Involved tooth with prosthesis.
20. 20.Endodontically involved/ RCT treated tooth
21. 21.Tooth with cervical abrasion / undetectable CEJ/ carious. The sample size was calculated using G\*Power software to achieve 80% statistical power for detecting a significant correlation of r = 0.5 using a linear regression model based on the previously conducted prospective study. The analysis indicated that 26 patients were required. To compensate for an anticipated 10% dropout rate, the sample size was increased, resulting in a final required sample size of 30 participants.

Conditions

Gingival Recessions

Keywords

keratinized tissue width; attached gingiva width; RT 1 gingival recession defect

Outcome Measures

Primary Outcomes (1)

• root coverage

  root coverage will be calculated in percentage

  6 months

Study Arms (1)

treatment of RT1 gingival recession defects using VISTA with connective tissue graft

EXPERIMENTAL

Procedure: Vestibular incision subperiosteal tunnel access with connective tissue graft in treating RT 1 gingival recession defects

Interventions

Vestibular incision subperiosteal tunnel access with connective tissue graft in treating RT 1 gingival recession defects PROCEDURE

the aim of this prospective clinical study is to determine if anatomical factors such as keratinized tissue width and attached gingiva width influence recession defects coverage of RT1 recession treated with minimally invasive surgical technique along with connective tissue graft. Keratinized tissue width and attached gingiva width are considered important for maintaining gingival health and long-term stability after root coverage. However, there is limited and unclear evidence on how much keratinized or attached gingiva is actually needed for successful root coverage. Most previous studies have focused on soft tissue thickness rather than these parameters.

treatment of RT1 gingival recession defects using VISTA with connective tissue graft

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with Millers class Ⅰ and II / RT1 isolated recession defects in labial maxillary and mandibular anterior teeth region.
• Recession depth ≥2mm
• Systemically healthy individuals.
• Age \>18 years old.
• Full mouth bleeding and plaque score ≤20%
• Patients who agreed to participate in the study and signed an informed consent form.

You may not qualify if:

• Patients having systemic disease such as hypertension, diabetes, hyperthyroidism or on medication that influence the outcome of periodontal therapy.
• Patient with active periodontal disease
• Smokers and tobacco users
• Mal-aligned anterior teeth.
• Patients who had already undergone root coverage procedure on the selected site.
• Pregnant and lactating females
• Involved tooth with trauma from occlusion.
• Involved tooth with prosthesis.
• Endodontically involved/ RCT treated tooth
• Tooth with cervical abrasion / undetectable CEJ/ carious

Sponsors & Collaborators

• Postgraduate Institute of Dental Sciences Rohtak: lead

Study Sites (1)

Post Graduate Institute of Dental Sciences

Rohtak, Haryana, 124001, India

Location

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Periodontal Atrophy

Study Officials

• Richa Tirkey

  PGIDS Rohtak

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Shikha Tewari, MDS

CONTACT

+919416514600; drshikhatewari@yahoo.com

Tewari

CONTACT

richatirkey16@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 2, 2026
• First Posted: May 8, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: May 8, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

IN (1)