NCT07576361

Completed

Impact of Microbiome in Endometriosis Development

Centre Hospitalier Universitaire de la Guadeloupe Source

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Other study identifiers

Sponsor study identifier

PAP_RI2_2019/04

Study Type

observational

Actual enrollment (reported)

48

Locations

1 country

Sites

1

Timeline

Study Start

November 25, 2020

Actual (reported)

Primary Completion

November 17, 2021

Actual (reported)

Study Completion

November 17, 2021

Actual (reported)

Brief Summary

Endometriosis is a chronic disease, of which the pathophysiology is still unknown. Several theories exist, the one of menstrual blood flow has been retained until now but does not fully explain it. The main symptoms are dysmenorrhea, dyspareunia and infertility. The aim of this study is to evaluate the impact of c.albicans colonization of vaginal microbioma in development of endometriosis

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 48 participants
Study completion date: November 17, 2021
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
November 25, 2020
Actual (reported)
Primary Completion
November 17, 2021
Actual (reported)
Study Completion
November 17, 2021
Actual (reported)
First Submitted
May 4, 2026
Actual (reported)
First Posted
May 8, 2026
Actual (reported)

Last Updated: May 8, 2026
Status Verified: May 2026
Last Update Submitted: May 4, 2026

Conditions

Endometriosis

Keywords

C.Albicansdysbiosisendometriosisinflammation

Outcome Measures

Primary Outcomes (1)

vaginal dysbiosis with C. albicans
comparison of percentages between the two groups
At inclusion

Secondary Outcomes (4)

correlation between vaginal dysbioses and the presence of Candida hyphae
At inclusion
impact of endometriosis on HPVhr carrying
At inclusion
inflammatory biological markers involved in the endometriotic process
At inclusion
inflammatory biological markers involved in the endometriotic process
At inclusion

Study Arms (2)

case

Patient with confirmed or highly suspected endometriosis

Control

No confirmed or highly suspected endometriosis

Eligibility Criteria

Age18 Years - 50 Years

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64)

Sampling MethodProbability Sample

Study Population

women aged 18-50 years old

You may qualify if:

For cases :

Sponsors & Collaborators

Centre Hospitalier Universitaire de la Guadeloupe
Otherlead

Study Sites (1)

Centre Hospitalier Universitaire de la Guadeloupe

Les Abymes, Guadeloupe, 97159, Guadeloupe

Biospecimen

Retention: SAMPLES WITHOUT DNA

vaginal samples, buccal samples

MeSH Terms

Conditions

EndometriosisDysbiosisInflammation

Condition Hierarchy (Ancestors)

Genital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

GÜLEN AYHAN, Doctor
CHU de la Guadeloupe
PRINCIPAL INVESTIGATOR

Enrollment

48 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

May 4, 2026

First Posted

May 8, 2026

Study Start

November 25, 2020

Actual (reported)

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Unknown

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Completed

NCT04846582

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Completed

NCT04159740

Microbiome and Immunologic Analysis - Women With Endometriosis

Completed

NCT03860909

Pelvic Endometriosis: Correlation of US and MRI With Laparoscopic Findings

Unknown

NCT04565470

Strategies of Self-management of Endometriosis Symptoms

Completed

aged 18-50 years old With confirmed or highly suspected endometriosis Affiliated to a social security system For controls: -aged 18-50 years old No confirmed or highly suspected Affiliated to a social security system

You may not qualify if:

Minors; Pregnant women; Protected persons, or persons placed under the protection of justice; Refusal to participate

Contact the study team to confirm eligibility.

Primary Completion

November 17, 2021

Actual (reported)

Study Completion

November 17, 2021

Actual (reported)

Last Updated

May 8, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT07576361
Data provider: ClinicalTrials.gov
Source updated: 2026-05-08
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:24:43 UTC

Locations

GP(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

case

Control

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations