Incidence of Different Surgical Technics for Colorectal Deep Infiltrating EndoMetriosis on the Post-operative Fertility and Pregnancy Outcomes

NCT04681898 | Completed

• 1 other identifier: 8088
• Study Type: observational
• Target: 164
• Locations: 1 country
• Sites: 1

Brief Summary

Endometriosis is a disease that is very present on the current media scene. Its symptoms are very nonspecific and numerous. (dysmenorrhea, dyspareunia, dyschezia, urinary functional signs, infertility, chronic pelvic pain, etc.) Its prevalence is estimated at 10% of women and 20% of them have deep pelvic endometriosis. Colorectal lesions involving the rectosigmoid junction and the rectum represent the most severe forms and affect 5.3 to 12% of patients with deep pelvic endometriosis. Endometriosis is found in 20 to 50% of patients consulting for infertility and the rate of spontaneous pregnancy in patients with deep endometriosis is estimated to be between 8.7 and 13%. Surgery appears to improve fertility in women. However, several surgical techniques for deep endometriosis at the digestive level have been described, conservative or radical, without any having demonstrated its superiority both in terms of symptoms and fertility. The aim of this study was to evaluate the incidence of different surgical technics (shaving vs. bowel resection) on post-operative fertility among patients with bowel deep infiltrating endometriosis and the pregnancy outcome

Conditions

Endometriosis

Keywords

colorectal endometriosis; deep infiltrating endometriosis; fertility; surgical technics in endometriosis

Outcome Measures

Primary Outcomes (1)

• Retrospective analysis of the rate of occurrence of pregnancy postoperatively.

  Files analysed retrospectily from September 1st, 2009 to October 31, 2016 will be examined

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult woman with a desire to become pregnant and who had undergone surgery for the management of deep digestive endometriosis between September 01, 2009 and October 31, 2016.

You may qualify if:

• Adult woman (≥18 years old).
• woman with a desire to become pregnant and who had undergone surgery for the management of deep digestive endometriosis between September 01, 2009 and October 31, 2016.
• Woman who has not expressed, after information, the reuse of her data for the purposes of this research.

You may not qualify if:

• Woman who expressed her opposition to participating in the study
• Woman who had undergone a surgical intervention for the management of deep digestive endometriosis between September 01, 2009 and October 31, 2016 and having no desire to become pregnant
• Woman under safeguard of justice
• Woman under guardianship or guardianship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Department of Gynecology - Strasbourg University Hospitals

Strasbourg, 67091, France

Location

MeSH Terms

Conditions

Endometriosis

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Study Officials

• Émilie FALLER

  Department of Gynecology - Strasbourg University Hospitals

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 18, 2020
• First Posted: December 23, 2020
• Study Start: December 30, 2020
• Primary Completion: November 30, 2021
• Study Completion: December 31, 2021
• Last Updated: January 31, 2022

Record last verified: 2020-11

Locations

FR (1)