NCT07576114

Brief Summary

The study design would be a Randomized Controlled Trial.This study would include a total 40 participants. 20 participants in each group. Sample size is obtained through G-power. The study duration will be 12 months after the approval from the research board. Non-probability convenience sampling will be used. Randomization will be done through sealed envelope method. The study will be conducted from Quaid-e-Azam Hospital Rawalpindi and Margalla Rehabilitation Centre.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Dec 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress89%
Dec 2025May 2026

Study Start

First participant enrolled

December 5, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 4, 2026

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 5, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 8, 2026

Completed
20 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 28, 2026

Expected
Last Updated

May 8, 2026

Status Verified

May 1, 2026

Enrollment Period

5 months

First QC Date

May 4, 2026

Last Update Submit

May 4, 2026

Conditions

Keywords

Dead Butt SyndromeGluteal Muscle ActivationCore Strengthening

Outcome Measures

Primary Outcomes (4)

  • Tampa Scale of Kinesiophobia (TSK-11)

    The Tampa Scale for Kinesiophobia (TSK-11) is a shortened, 11-item version of the original 17-item TSK questionnaire used to assess fear of movement, or kinesiophobia, in individuals with chronic pain or other conditions involving movement limitations

    4 weeks

  • Lower Extremity Functional Scale (LEFS)

    The Lower Extremity Functional Scale (LEFS) is used to assess "patients' initial function, ongoing progress, and outcome" for a variety of disorders affecting the lower extremities. LEFS is a self-reported survey. The LEFS total score ranges from 0 to 80, with higher scores indicating better functional ability.

    4 weeks

  • Numeric Pain Rating Scale

    The Numeric Pain Rating Scale (NPRS) is a tool used to measure the intensity of pain. It's a unidimensional scale, typically an 11-point scale ranging from 0 to 10, where 0 represents no pain and 10 represents the worst pain imaginable. Patients verbally or numerically indicate the level of pain they are experiencing.

    4 Weeks

  • The Trendelenburg test

    The Trendelenburg test is a physical examination used to assess the strength of hip abductor muscles, specifically the gluteus medius and gluteus minimus, or to check for the competency of venous valves in the legs. A positive Trendelenburg sign, indicated by a drop of the pelvis on the unsupported side during a single-leg stance, suggests weakness in the hip abductors.

    4 Weeks

Study Arms (2)

Group A: Gluteal Activation

EXPERIMENTAL
Other: Group A: Gluteal Muscle Activation

Active comparator

ACTIVE COMPARATOR

Group B - Gluteal Muscle Activation Program + Core Strengthening Program Hot pack applied to lumbar area for 15-20 minutes. 3 sessions per week for 4 weeks. Moderate intensity, bodyweight-based exercises with controlled movement. Each exercise: 3 sets of 15 repetitions with 30-40 seconds rest between sets. Target: Gluteal muscles and pelvic control:

Other: Group B: Gluteal Muscle Activation and Core stregthening exercises

Interventions

Gluteal Activation focuses on "waking up" and isolating the gluteus maximus, medius, and minimus to ensure they fire properly, often using low-load, high-control movements.

Group A: Gluteal Activation

Gluteal Activation focuses on "waking up" and isolating the gluteus maximus, medius, and minimus to ensure they fire properly, often using low-load, high-control movements.Core Strengthening focuses on stabilizing the spine and pelvis by targeting the abdominals, back, and deep pelvic muscles.

Active comparator

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Symptoms persisting for more than 6 weeks (subacute or chronic cases).
  • Sedentary to moderately active individuals (i.e., not involved in heavy gluteal-strengthening or core training for at least 3 months prior to the study). vParticipants will be diagnosed with Dead Butt Syndrome based on the presence of at least two out of three of the following criteria:
  • Self-reported dull ache, discomfort, or tightness in the gluteal region worsened with prolonged sitting or walking.
  • Positive Trendelenburg Test
  • ≤ 4/5 on the standard MRC grading scale

You may not qualify if:

  • Pregnancy or plans to become pregnant during the study period.
  • Diagnosed hip labral tears, piriformis syndrome, or sciatica unrelated to gluteal amnesia.
  • Degenerative or neurological conditions such as osteoarthritis, multiple sclerosis, stroke, or spinal cord injury.
  • History of significant spinal trauma or surgery in the past 12 months.
  • Engagement in regular physical exercise or participation in rehabilitation programs within the last 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Riphah University Islamabad

Islamabad, Pakistan

RECRUITING

MeSH Terms

Conditions

Syndrome

Condition Hierarchy (Ancestors)

DiseasePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Attiq Ur Rehman, MS

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

REHMAT KHATOON, MS-OMPT

CONTACT

Attiq ur Rehman Physiotherapist, MS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 4, 2026

First Posted

May 8, 2026

Study Start

December 5, 2025

Primary Completion

May 5, 2026

Study Completion (Estimated)

May 28, 2026

Last Updated

May 8, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations