NCT00213447

Brief Summary

immunological study of the T cell repertoire phenotype and functionality in hypersensitivity syndrome.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2002

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2002

Completed
2.9 years until next milestone

First Submitted

Initial submission to the registry

September 13, 2005

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 21, 2005

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2005

Completed
Last Updated

June 18, 2013

Status Verified

June 1, 2013

First QC Date

September 13, 2005

Last Update Submit

June 17, 2013

Conditions

HypersensitivitySyndrome

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with Drug rash with eosinophilia and systemic symptoms

You may qualify if:

  • age \> 18
  • cutaneous eruption
  • lymph nodes
  • hepatitis
  • interstitial pneumonia
  • nephritis
  • cardiopathy
  • eosinophilia
  • hyperlymphocytosis

You may not qualify if:

  • age minor to 18
  • HIV +

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UH-Rouen

Rouen, France

Location

Related Publications (1)

  • Picard D, Janela B, Descamps V, D'Incan M, Courville P, Jacquot S, Rogez S, Mardivirin L, Moins-Teisserenc H, Toubert A, Benichou J, Joly P, Musette P. Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response. Sci Transl Med. 2010 Aug 25;2(46):46ra62. doi: 10.1126/scitranslmed.3001116.

    PMID: 20739682DERIVED

MeSH Terms

Conditions

HypersensitivitySyndrome

Condition Hierarchy (Ancestors)

Immune System DiseasesDiseasePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Pascal Joly, MD-PHD

    UH rouen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 13, 2005

First Posted

September 21, 2005

Study Start

November 1, 2002

Study Completion

December 1, 2005

Last Updated

June 18, 2013

Record last verified: 2013-06

Locations

FR(1)