NCT07573553

Brief Summary

This randomized controlled trial aims to evaluate the effectiveness of rib mobilization combined with postural correction exercises in reducing pain, improving cervical posture, and enhancing rib and thoracic mobility among individuals with Upper Crossed Syndrome (UCS). A total of 64 participants aged 20-45 years will be recruited and randomly assigned to two groups: Group A (rib mobilization + postural correction) and Group B (postural correction only). Intervention will be provided for 4-6 weeks, three sessions per week. Outcomes will include pain (VAS), cervical posture (inclinometer), and rib/thoracic mobility (tape measure). Data will be analyzed using SPSS version 26.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
2mo left

Started Oct 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress80%
Oct 2025Jun 2026

Study Start

First participant enrolled

October 16, 2025

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

April 30, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 7, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 28, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 28, 2026

Last Updated

May 7, 2026

Status Verified

April 1, 2026

Enrollment Period

9 months

First QC Date

April 30, 2026

Last Update Submit

April 30, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Pain Intensity

    1\. Pain Intensity - Measured using the Visual Analog Scale (VAS) ranging from 0 (no pain) to 10 (worst pain).

    1 year

  • Cervical Posture

    Cervical Posture - Measured using an inclinometer to determine the craniovertebral angle.

    1 year

  • Rib/Thoracic Mobility

    Rib/Thoracic Mobility - Measured using a tape measure and inclinometer to assess rib cage expansion and thoracic extension.

    1 year

Study Arms (2)

Intervention group

EXPERIMENTAL

Group receiving Rib Mobilization + Postural Correction Exercises

Behavioral: Rib Mobilization and Postural Correction Exercises

Control group

ACTIVE COMPARATOR

Group receiving Postural Correction Exercises Only

Other: Postural Correction Exercises Only

Interventions

Participants will receive Grade I-III rib mobilizations at the costovertebral and costotransverse joints (ribs 2-6) along with thoracic central posterior-anterior mobilizations. In addition, postural correction exercises including scapular retraction, deep neck flexor training, pectoralis stretching, and thoracic extension exercises will be performed. Each session will last 30-40 minutes, three times per week for 4-6 weeks.

Intervention group

Participants will perform only postural correction exercises, including scapular retraction, deep neck flexor training, pectoralis stretching, and thoracic extension exercises. Sessions will last 30-40 minutes, three times per week for 4-6 weeks.

Control group

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 20 to 45 years
  • Forward head posture (craniovertebral angle \< 50°)
  • Cervical pain or discomfort for ≥4 weeks
  • Moderate pain intensity (VAS 3-6)
  • Willingness to participate and provide informed consent
  • Clinically diagnosed Upper Crossed Syndrome (UCS)
  • Meets Asian Fitness Society diagnostic criteria for UCS

You may not qualify if:

  • History of trauma or surgery to cervical/thoracic spine
  • Cervical disc herniation, radiculopathy, or neurological deficits
  • Structural deformities (scoliosis, Scheuermann's disease)
  • Systemic musculoskeletal disorders (e.g., rheumatoid arthritis)
  • Vestibular, balance, or visual disorders
  • Recent similar therapy within 3 months
  • Pregnancy or contraindication to manual therapy
  • Ongoing use of pain medications or muscle relaxants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

District Headquater Haripur

Chak Six Hundred Twenty-four, Khyber Pakhtunkhwat, 22620, Pakistan

RECRUITING

Related Publications (4)

  • Sepehri S, Sheikhhoseini R, Piri H, Sayyadi P. The effect of various therapeutic exercises on forward head posture, rounded shoulder, and hyperkyphosis among people with upper crossed syndrome: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2024 Feb 1;25(1):105. doi: 10.1186/s12891-024-07224-4.

    PMID: 38302926BACKGROUND
  • Bayattork M, Skold MB, Sundstrup E, Andersen LL. Exercise interventions to improve postural malalignments in head, neck, and trunk among adolescents, adults, and older people: systematic review of randomized controlled trials. J Exerc Rehabil. 2020 Feb 26;16(1):36-48. doi: 10.12965/jer.2040034.017. eCollection 2020 Feb.

    PMID: 32161733BACKGROUND
  • Chang MC, Choo YJ, Hong K, Boudier-Reveret M, Yang S. Treatment of Upper Crossed Syndrome: A Narrative Systematic Review. Healthcare (Basel). 2023 Aug 17;11(16):2328. doi: 10.3390/healthcare11162328.

    PMID: 37628525BACKGROUND
  • Arshadi R, Ghasemi GA, Samadi H. Effects of an 8-week selective corrective exercises program on electromyography activity of scapular and neck muscles in persons with upper crossed syndrome: Randomized controlled trial. Phys Ther Sport. 2019 May;37:113-119. doi: 10.1016/j.ptsp.2019.03.008. Epub 2019 Mar 21.

    PMID: 30928841BACKGROUND

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type Preus

Study Officials

  • Attiq Ur Rehman, MS

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Altamash Hussain Khan, DPT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 30, 2026

First Posted

May 7, 2026

Study Start

October 16, 2025

Primary Completion (Estimated)

June 28, 2026

Study Completion (Estimated)

June 28, 2026

Last Updated

May 7, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations