NCT07571382

Brief Summary

Taste, smell, trigeminal and salivary function is impacted in post-COVID-19 patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
176

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2021

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2021

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 25, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 25, 2023

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

April 27, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 6, 2026

Completed
Last Updated

May 6, 2026

Status Verified

May 1, 2026

Enrollment Period

2.1 years

First QC Date

April 27, 2026

Last Update Submit

May 4, 2026

Conditions

Smell DysfunctionTaste DysfunctionTrigeminal DysfunctionSalivary Dysfunction

Keywords

SmellTasteTrigeminusSalivation

Outcome Measures

Primary Outcomes (1)

  • Smell

    Olfactory (smell) function will be evaluated using the Twelve felt-tip Sniffin' Sticks test (Burghart Messtechnik GmbH, Holm, Germany). Participants are categorized into anosmic (score 0-6, no smell), hyposmic (score 7-10, reduced smell), and normosmic (score 11-12, normal smell), according to normative classification.

    two years

Secondary Outcomes (3)

  • Taste

    2 years

  • Dry mouth

    2 years

  • Dysesthesia

    2 years

Study Arms (1)

Parosmia

OTHER

Parosmia

Other: Smell training

Interventions

Smell trainingOTHER

Smell training

Parosmia

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • COVID-19 diagnosis

You may not qualify if:

  • Not COVID-19 diagnosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Oslo

Oslo, Oslo, 0455, Norway

Location

MeSH Terms

Conditions

Olfaction DisordersTaste DisordersAnosmiaSialorrhea

Interventions

Olfactory Training

Condition Hierarchy (Ancestors)

Sensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsSalivary Gland DiseasesMouth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

Therapeutics

Study Officials

  • Per Ole Iversen, PhD

    Per Ole Iversen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SCREENING
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 27, 2026

First Posted

May 6, 2026

Study Start

April 1, 2021

Primary Completion

April 25, 2023

Study Completion

April 25, 2023

Last Updated

May 6, 2026

Record last verified: 2026-05

Locations

NO(1)