NCT07570030

Brief Summary

The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2025

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2025

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

April 28, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 6, 2026

Completed
Last Updated

May 6, 2026

Status Verified

April 1, 2026

Enrollment Period

Same day

First QC Date

April 28, 2026

Last Update Submit

April 28, 2026

Conditions

Performance Enhancement

Keywords

firefighters

Outcome Measures

Primary Outcomes (1)

  • firefighting balance test

    Measure the time it takes to return

    15 minutes after intervention

Study Arms (2)

intervention

ACTIVE COMPARATOR

Chewing caffeine gum for 10 minutes

Dietary Supplement: Caffeine (300 mg)Other: Placebo

placebo

PLACEBO COMPARATOR

Chewing placebo gum for 10 minutes

Dietary Supplement: Caffeine (300 mg)Other: Placebo

Interventions

PlaceboOTHER

The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes.

interventionplacebo
Caffeine (300 mg)DIETARY_SUPPLEMENT

The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes.

interventionplacebo

Eligibility Criteria

Age20 Years - 40 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsOnly male subjects
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Active-duty members of the Special Search and Rescue Brigade
  • Regularly perform firefighting and disaster relief duties
  • Have fully recovered from sports injuries such as strains or sprains for at least 3 months

You may not qualify if:

  • Members who are not part of the Special Search and Rescue Brigade.
  • Individuals who do not regularly perform firefighting and disaster relief duties
  • Participants who have not fully recovered from sports injuries for at least 3 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University of Sport

Taichung, North, 404, Taiwan

Location

MeSH Terms

Interventions

Caffeine

Intervention Hierarchy (Ancestors)

XanthinesAlkaloidsHeterocyclic CompoundsPurinonesPurinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-Ring

Study Officials

  • Chih Hui Chiu

    National Taiwan University of Sport

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 28, 2026

First Posted

May 6, 2026

Study Start

July 1, 2025

Primary Completion

July 1, 2025

Study Completion

November 25, 2025

Last Updated

May 6, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

TW(1)