Social Optimization Study

NCT07564960 | Not Yet Recruiting DMC

• 1 other identifier: STUDY00007008
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study tests whether clinical interventions to optimize support receptivity lead to improvements in social integration and quality of life (QOL) amongst long-term lung cancer survivors. The feasibility and acceptability of the intervention and assessment procedures will be examined. Thirty long-term lung cancer survivors will be randomized to a support receptivity intervention or an attention-control condition. Our intervention draws on cognitive behavioral therapy (CBT) strategies to reduce social anxiety, improve social awareness, and promote social integration. We will use two novel in vivo sampling methods using a mobile phone platform to assess social engagement and QOL improvements: 1) recording via the Electronically Activated Recorder to capture daily social interactions, and 2) repeated self-report sampling where participants answer questions about their social engagement experiences via their personal cell phone.

Conditions

Lung Cancer

Keywords

Social support; Psycho-oncology; Lung neoplasms

Outcome Measures

Primary Outcomes (2)

• Feasibility assessed by recruitment and retention rates

  Given the pilot nature of this work, the intervention/study will be deemed feasible if 20% of eligible potential participants approached enroll and 50% of enrolled participants are retained at post-intervention

  Throughout the recruitment period

• Acceptability assessed by study-specific survey after the intervention

  The intervention/study will be deemed acceptable if, on average, participants report satisfaction with the overall program/study as ≥2 on a 0-4 scale.

  3 weeks - immediately after the intervention

Secondary Outcomes (6)

• Change in quality of life (QOL) using the SF-36 from baseline to immediately after the intervention.

  3 weeks - immediately after the intervention

• Change in Perceived Stress using the Perceived Stress Scale (PSS) from baseline to immediately after the intervention

  3 weeks - immediately after the intervention

• Change in depression using the CES-D scale from baseline to immediately after the intervention

  3 weeks - immediately after the intervention

• Change in network diversity using the Berkman-Syme Social Network Index (BS-SNI) from baseline to immediately after the intervention

  3 weeks - immediately after the intervention

• Change in subject loneliness and social isolation using the UCLA-Loneliness Scale from baseline to immediately after the intervention

  3 weeks - immediately after the intervention

Study Arms (2)

Social support receptivity training

EXPERIMENTAL

Participants will receive a 3-week, 6 session CBT intervention targeting cognitive awareness of prosocial cues coupled with behavioral activation and social skills training to improve target person social engagement.

Behavioral: Social support receptivity training

Social awareness training

ACTIVE COMPARATOR

Participants receiving a 3-week, 6 session program designed to increase awareness of the social support already available to them.

Behavioral: Social awareness training

Interventions

Social support receptivity training BEHAVIORAL

A 3-week, 6-session CBT intervention that targets cognitive awareness of prosocial cues and leverages behavioral activation and social skills training

Social support receptivity training

Social awareness training BEHAVIORAL

A 3-week, 6 session program designed to increase awareness of available social support.

Social awareness training

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults (18 Years or Older)
• History of lung cancer
• at least 12 months since cancer diagnosis
• fluent in English
• able to attend virtually or in person sessions at the University of Arizona.

You may not qualify if:

• Less than 12 months of cancer diagnosis at time of enrollment
• undergoing treatment for mood or anxiety health issues at time of enrollment
• unable to provide informed consent.

Sponsors & Collaborators

• University of Arizona: lead

Study Sites (1)

University of Arizona Mel and Enid Zuckerman College of Public Health

Tucson, Arizona, 85719, United States

Location

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Scott Carvajal, PhD, MPH

  University of Arizona

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Francis Morales-Lozada

CONTACT

(520) 621-0563; fmoraleslozada@arizona.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 27, 2026
• First Posted: May 4, 2026
• Study Start: April 29, 2026
• Primary Completion (Estimated): June 13, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: May 4, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)